SCHEMBL21034864

SCHEMBL21034864

c1ccc(-n2c3ccccc3c3ccc(-c4ccc5c(c4)c4ccccc4c4c6ccccc6c6ccccc6c54)cc32)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.58
KDM4E B2RXH2 1/20 0.58
ATM Q13315 1/20 0.58
KMT2A Q03164 3/20 0.38
MAPK1 P28482 1/20 0.38
IL1R1 P14778 1/20 0.38
HDAC4 P56524 1/20 0.37
ALDH1A1 P00352 3/20 0.37
MEN1 O00255 2/20 0.37
MAPT P10636 1/20 0.37
HTT P42858 1/20 0.37
RXRA P19793 1/20 0.37
RXRB P28702 1/20 0.37
POLB P06746 1/20 0.36
TSHR P16473 1/20 0.36
BRCA1 P38398 1/20 0.36
HSD17B10 Q99714 1/20 0.36
MAPK8 P45983 2/20 0.35
RXFP1 Q9HBX9 1/20 0.34
PGR P06401 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21034866 1.00 L3MBTL1 (0.58) L3MBTL1KDM4EATMKMT2AMAPK1
SCHEMBL21035247 0.98 L3MBTL1 (0.56) L3MBTL1KDM4EATMKMT2AMAPK1
SCHEMBL21034865 0.97 L3MBTL1 (0.55) L3MBTL1KDM4EATMKMT2AMAPK1
SCHEMBL21035245 0.97 L3MBTL1 (0.55) L3MBTL1KDM4EATMKMT2AMAPK1
SCHEMBL12716554 0.95 L3MBTL1 (0.64) L3MBTL1KDM4EATMKMT2AMAPK1
SCHEMBL21034875 0.94 L3MBTL1 (0.58) L3MBTL1KDM4EATMKMT2AMAPK1
SCHEMBL21034874 0.94 L3MBTL1 (0.58) L3MBTL1KDM4EATMKMT2AMAPK1
SCHEMBL21035230 0.94 L3MBTL1 (0.48) L3MBTL1KDM4EATMKMT2AMAPK1
SCHEMBL17229066 0.93 L3MBTL1 (0.62) L3MBTL1KDM4EATMKMT2AMAPK1
SCHEMBL21036076 0.92 L3MBTL1 (0.53) L3MBTL1KDM4EATMKMT2AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230096132-A1 CYCLOALKANE-FUSED POLYCYCLIC AROMATIC COMPOUND KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-03-30 US disclosed
US-20190165279-A1 ORGANIC ELECTROLUMINESCENT ELEMENT JNC CORPORATION (JP) 2019-05-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230096132-A1 CYCLOALKANE-FUSED POLYCYCLIC AROMATIC COMPOUND LAGE3, ELOC, ELOB L3MBTL1 280/4885KDM4E 1841/4885ATM 3575/4885
US-20190165279-A1 ORGANIC ELECTROLUMINESCENT ELEMENT TCF4, LGR4, OR51E2 L3MBTL1 834/4885KDM4E 396/4885ATM 1673/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.