Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 6/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 6/20 | 0.41 |
| ▸ | MMP9 | P14780 | 4/20 | 0.41 |
| ▸ | MMP2 | P08253 | 4/20 | 0.41 |
| ▸ | MMP1 | P03956 | 6/20 | 0.40 |
| ▸ | MMP3 | P08254 | 5/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.40 |
| ▸ | MMP7 | P09237 | 4/20 | 0.39 |
| ▸ | MMP13 | P45452 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | CCR3 | P51677 | 1/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21035654 | 1.00 | HCRTR1 (0.41) | HCRTR1HCRTR2MMP9MMP2MMP1 | |
| SCHEMBL21035398 | 0.89 | HTR1A (0.42) | HCRTR1HCRTR2MMP9MMP1MMP3 | |
| SCHEMBL21035317 | 0.89 | HTR1A (0.42) | HCRTR1HCRTR2MMP9MMP1MMP3 | |
| SCHEMBL21035402 | 0.87 | MMP1 (0.43) | HCRTR1HCRTR2MMP9MMP2MMP1 | |
| SCHEMBL21035318 | 0.87 | MMP1 (0.43) | HCRTR1HCRTR2MMP9MMP2MMP1 | |
| SCHEMBL21035522 | 0.87 | MMP1 (0.43) | HCRTR1HCRTR2MMP9MMP2MMP1 | |
| SCHEMBL21036273 | 0.86 | MMP9 (0.42) | HCRTR1HCRTR2MMP9MMP2MMP1 | |
| SCHEMBL21035405 | 0.86 | MMP9 (0.42) | HCRTR1HCRTR2MMP9MMP2MMP1 | |
| SCHEMBL21034979 | 0.84 | MMP1 (0.45) | HCRTR1HCRTR2MMP9MMP2MMP1 | |
| SCHEMBL21034981 | 0.84 | MMP1 (0.45) | HCRTR1HCRTR2MMP9MMP2MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019104011-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2019-05-31 | — | — | WO | disclosed |