SCHEMBL21036274

CC(C)(C)OC(=O)NC1CC2CCC(C1)C2C(=O)[C@@H]1C[C@H](Oc2ccc(Cl)c(Oc3ccccc3)c2)CN1S(=O)(=O)c1ccc2cc(OC3CCCC3)ccc2c1

nearest known ligand 0.35

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	MMP9	P14780	4/20	0.35

▸	KMT2A	Q03164	1/20	0.34

▸	L3MBTL1	Q9Y468	1/20	0.34

▸	MCL1	Q07820	8/20	0.34

▸	MMP2	P08253	2/20	0.34

▸	MMP1	P03956	2/20	0.34

▸	MMP3	P08254	2/20	0.34

▸	MMP7	P09237	2/20	0.34

▸	BCL2	P10415	2/20	0.33

▸	BCL2L1	Q07817	2/20	0.33

▸	BTK	Q06187	1/20	0.33

▸	GCK	P35557	2/20	0.33

▸	CCR4	P51679	2/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL21035656	0.90	MCL1 (0.37)	MMP9KMT2AL3MBTL1MCL1MMP2
SCHEMBL21035406	0.89	KMT2A (0.36)	MMP9KMT2AL3MBTL1MCL1MMP2
SCHEMBL21035405	0.82	MMP9 (0.42)	MMP9MMP2MMP1MMP3MMP7
SCHEMBL21036273	0.82	MMP9 (0.42)	MMP9MMP2MMP1MMP3MMP7
SCHEMBL21036271	0.82	MMP9 (0.42)	MMP9MMP1MMP3MMP7
SCHEMBL21035520	0.81	L3MBTL1 (0.39)	MMP9KMT2AL3MBTL1MCL1MMP2
SCHEMBL21034983	0.80	MCL1 (0.38)	MMP9KMT2AL3MBTL1MCL1MMP2
SCHEMBL21035354	0.78	MCL1 (0.39)	MMP9KMT2AL3MBTL1MCL1MMP2
SCHEMBL21034978	0.78	MCL1 (0.39)	MMP9KMT2AL3MBTL1MCL1MMP2
SCHEMBL21035524	0.78	KAT6A (0.38)	MMP9MMP2MMP1MMP3MMP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2019104011-A1	CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE	BIOMARIN PHARMACEUTICAL INC. (US)	2019-05-31	—	—	WO	disclosed