Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 6/20 | 0.39 |
| ▸ | MMP13 | P45452 | 5/20 | 0.39 |
| ▸ | MMP9 | P14780 | 3/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP7 | P09237 | 1/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 4/20 | 0.39 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.38 |
| ▸ | MLNR | O43193 | 1/20 | 0.37 |
| ▸ | MDH1 | P40925 | 1/20 | 0.37 |
| ▸ | MDH2 | P40926 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21035570 | 0.98 | MMP1 (0.40) | SCN9AMMP1MMP13MMP9MMP3 | |
| SCHEMBL21035508 | 0.94 | SCN9A (0.41) | SCN9AMMP1MMP13MMP9MMP3 | |
| SCHEMBL21035503 | 0.94 | EPHX2 (0.39) | MMP1MMP13MMP9MMP3MMP7 | |
| SCHEMBL21034944 | 0.94 | PRKAA2 (0.40) | MMP1MMP13MMP9MMP3MMP7 | |
| SCHEMBL21035340 | 0.93 | MEN1 (0.41) | MMP1MMP13MMP9MMP3MMP7 | |
| SCHEMBL21035442 | 0.93 | MEN1 (0.41) | MMP1MMP13MMP9MMP3MMP7 | |
| SCHEMBL21035600 | 0.93 | MEN1 (0.41) | MMP1MMP13MMP9MMP3MMP7 | |
| SCHEMBL21034960 | 0.90 | GPR119 (0.40) | SCN9AMMP1MMP13MMP9MMP3 | |
| SCHEMBL21035486 | 0.89 | MMP13 (0.39) | MMP1MMP13MMP9MMP3MMP7 | |
| SCHEMBL21036241 | 0.89 | MMP13 (0.39) | MMP1MMP13MMP9MMP3MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019104011-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2019-05-31 | — | — | WO | disclosed |