Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | GHSR | Q92847 | 12/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 3/20 | 0.41 |
| ▸ | MMP9 | P14780 | 3/20 | 0.41 |
| ▸ | MMP13 | P45452 | 3/20 | 0.41 |
| ▸ | CPT2 | P23786 | 1/20 | 0.40 |
| ▸ | CPT1A | P50416 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 2/20 | 0.39 |
| ▸ | MMP7 | P09237 | 2/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.39 |
| ▸ | FNTB | P49356 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21035361 | 1.00 | LMNA (0.54) | LMNAMAPTNPSR1GHSRCNR1 | |
| SCHEMBL21035062 | 0.93 | LMNA (0.48) | LMNAMAPTNPSR1GHSRCNR1 | |
| SCHEMBL21035324 | 0.90 | LMNA (0.43) | LMNAMAPTNPSR1GHSRMMP1 | |
| SCHEMBL21035356 | 0.85 | LMNA (0.48) | LMNAMAPTNPSR1MMP1MMP9 | |
| SCHEMBL21035573 | 0.85 | LMNA (0.48) | LMNAMAPTNPSR1MMP1MMP9 | |
| SCHEMBL21001945 | 0.83 | GHSR (0.45) | LMNAMAPTNPSR1GHSRMMP1 | |
| SCHEMBL21035633 | 0.83 | GHSR (0.45) | LMNAMAPTNPSR1GHSRMMP1 | |
| SCHEMBL21002001 | 0.83 | GHSR (0.45) | LMNAMAPTNPSR1GHSRMMP1 | |
| SCHEMBL21002063 | 0.82 | PSEN1 (0.40) | LMNAMAPTNPSR1GHSRMMP1 | |
| SCHEMBL21035064 | 0.82 | LMNA (0.45) | LMNAMAPTNPSR1MMP1FNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019104011-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2019-05-31 | — | — | WO | disclosed |