Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MMP1 | P03956 | 6/20 | 0.45 |
| ▸ | MMP13 | P45452 | 6/20 | 0.45 |
| ▸ | MMP3 | P08254 | 6/20 | 0.45 |
| ▸ | MMP9 | P14780 | 5/20 | 0.45 |
| ▸ | MMP7 | P09237 | 5/20 | 0.45 |
| ▸ | FNTA | P49354 | 1/20 | 0.42 |
| ▸ | FNTB | P49356 | 1/20 | 0.42 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.42 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.42 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.41 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.41 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21035573 | 1.00 | LMNA (0.48) | LMNAMAPTNPSR1ALDH1A1KMT2A | |
| SCHEMBL21035063 | 0.93 | CACNA1A (0.44) | LMNAMAPTNPSR1ALDH1A1KMT2A | |
| SCHEMBL21035323 | 0.89 | HCRTR1 (0.43) | MAPTALDH1A1KMT2AMMP1MMP13 | |
| SCHEMBL21035581 | 0.85 | LMNA (0.54) | LMNAMAPTNPSR1MMP1MMP13 | |
| SCHEMBL21035361 | 0.85 | LMNA (0.54) | LMNAMAPTNPSR1MMP1MMP13 | |
| SCHEMBL21035064 | 0.84 | LMNA (0.45) | LMNAMAPTNPSR1KMT2AMMP1 | |
| SCHEMBL21035630 | 0.82 | CHRM2 (0.42) | NPSR1ALDH1A1KMT2AMMP1MMP13 | |
| SCHEMBL21035631 | 0.82 | CHRM2 (0.42) | NPSR1ALDH1A1KMT2AMMP1MMP13 | |
| SCHEMBL21035326 | 0.81 | MMP1 (0.42) | LMNAMAPTNPSR1ALDH1A1KMT2A | |
| SCHEMBL21035451 | 0.81 | HCRTR1 (0.41) | MAPTALDH1A1KMT2AMMP1MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019104011-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2019-05-31 | — | — | WO | disclosed |