Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | HTR7 | P34969 | 2/20 | 0.35 |
| ▸ | HTR5A | P47898 | 2/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 3/20 | 0.34 |
| ▸ | MMP1 | P03956 | 2/20 | 0.34 |
| ▸ | MMP3 | P08254 | 2/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21035612 | 1.00 | GHSR (0.38) | GHSRHTR1AHTR7HTR5AHTR1D | |
| SCHEMBL21035614 | 1.00 | GHSR (0.38) | GHSRHTR1AHTR7HTR5AHTR1D | |
| SCHEMBL21035403 | 0.89 | HTR1A (0.39) | GHSRHTR1AHTR7HTR5AHTR1D | |
| SCHEMBL21035319 | 0.89 | HTR1A (0.39) | GHSRHTR1AHTR7HTR5AHTR1D | |
| SCHEMBL21035619 | 0.88 | MMP9 (0.37) | MMP9MMP1MMP3ADAM17MMP2 | |
| SCHEMBL21035618 | 0.86 | CA12 (0.41) | HTR1AHTR7HTR5AHTR1DHTR1B | |
| SCHEMBL21034939 | 0.85 | HTR1A (0.42) | GHSRHTR1AHTR7HTR5AHTR1D | |
| SCHEMBL21035665 | 0.85 | HTR1A (0.42) | GHSRHTR1AHTR7HTR5AHTR1D | |
| SCHEMBL21034995 | 0.85 | HTR1A (0.42) | GHSRHTR1AHTR7HTR5AHTR1D | |
| SCHEMBL21035133 | 0.84 | HTR1A (0.41) | GHSRHTR1AHTR7HTR5AHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019104011-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2019-05-31 | — | — | WO | disclosed |