Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3343296 | 0.83 | PTGDR2 (0.54) | ABCB11PTGDR2NPSR1KDM4ECYP2C19 | |
| SCHEMBL2103120 | 0.81 | TSHR (0.47) | PTGDR2NPSR1KDM4ECYP2C19ALDH1A1 | |
| SCHEMBL2103586 | 0.73 | PTGDR2 (0.47) | ABCB11PTGDR2KDM4ECYP2C19USP2 | |
| SCHEMBL2101324 | 0.72 | ABCB11 (0.65) | ABCB11PTGDR2CYP2C9PPARG | |
| SCHEMBL2103588 | 0.69 | KDM4E (0.40) | PTGDR2KDM4ECYP2C19USP2ALDH1A1 | |
| SCHEMBL4007944 | 0.68 | MRGPRX4 (0.51) | PTGDR2KMT2AMRGPRX4 | |
| SCHEMBL30760989 | 0.68 | L3MBTL1 (0.47) | PTGDR2NPSR1KDM4ECYP2C19CYP1A2 | |
| SCHEMBL531737 | 0.68 | L3MBTL1 (0.47) | PTGDR2NPSR1KDM4ECYP2C19CYP1A2 | |
| SCHEMBL28037427 | 0.68 | PDE2A (0.36) | NPSR1KDM4ECYP2C19USP2ALDH1A1 | |
| SCHEMBL11238875 | 0.67 | TSHR (0.43) | KDM4ECYP2C19ALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163727-B2 | Biphenyloxyacetic acid derivatives for the treatment of respiratory disease | ASTRAZENECA AB (SE) | 2012-04-24 | — | — | US | disclosed |