Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 2/20 | 0.48 |
| ▸ | MMP9 | P14780 | 2/20 | 0.48 |
| ▸ | MMP13 | P45452 | 2/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | GHSR | Q92847 | 10/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP7 | P09237 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL21002053 | 0.97 | MMP1 (0.46) | MMP1MMP9MMP13PDE4BPDE4D | |
| Trifluoroacetic Acid SCHEMBL21002051 | 0.97 | MMP1 (0.46) | MMP1MMP9MMP13PDE4BPDE4D | |
| SCHEMBL21035497 | 0.92 | KCNH2 (0.43) | MMP1MMP9MMP13GHSR | |
| Trifluoroacetic Acid SCHEMBL21002100 | 0.90 | KCNH2 (0.41) | MMP1MMP9MMP13GHSRMMP3 | |
| Trifluoroacetic Acid SCHEMBL21002101 | 0.90 | KCNH2 (0.41) | MMP1MMP9MMP13GHSRMMP3 | |
| SCHEMBL21035106 | 0.88 | GHSR (0.47) | MMP1MMP9MMP13GHSRMMP3 | |
| SCHEMBL21036264 | 0.86 | MMP1 (0.47) | MMP1MMP9MMP13PDE4BPDE4D | |
| SCHEMBL21035534 | 0.82 | GHSR (0.55) | GHSR | |
| SCHEMBL21034936 | 0.80 | ADRB2 (0.43) | MMP1MMP9MMP13GHSRMMP3 | |
| SCHEMBL21035477 | 0.80 | ADRB2 (0.43) | MMP1MMP9MMP13GHSRMMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019104011-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2019-05-31 | — | — | WO | disclosed |