Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 4/20 | 0.47 |
| ▸ | MMP9 | P14780 | 4/20 | 0.47 |
| ▸ | MMP13 | P45452 | 3/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.40 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.39 |
| ▸ | WNT3 | P56703 | 3/20 | 0.38 |
| ▸ | SFRP1 | Q8N474 | 3/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | GHSR | Q92847 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 3/20 | 0.37 |
| ▸ | MMP7 | P09237 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21036265 | 0.86 | MMP1 (0.48) | MMP1MMP9MMP13PDE4BPDE4D | |
| SCHEMBL21035472 | 0.84 | MMP1 (0.49) | MMP1MMP9MMP13EPHX2NAMPT | |
| Trifluoroacetic Acid SCHEMBL21002051 | 0.84 | MMP1 (0.46) | MMP1MMP9MMP13PDE4BPDE4D | |
| Trifluoroacetic Acid SCHEMBL21002053 | 0.84 | MMP1 (0.46) | MMP1MMP9MMP13PDE4BPDE4D | |
| SCHEMBL21034935 | 0.82 | CCR4 (0.42) | MMP1MMP9MMP13PRKAA2WNT3 | |
| SCHEMBL21035077 | 0.81 | LMNA (0.39) | MMP1MMP9MMP13WNT3SFRP1 | |
| SCHEMBL21035117 | 0.81 | LMNA (0.39) | MMP1MMP9MMP13WNT3SFRP1 | |
| SCHEMBL21036266 | 0.80 | ITGB1 (0.40) | WNT3SFRP1EPHX2 | |
| SCHEMBL21035343 | 0.80 | CCR4 (0.42) | MMP1MMP9MMP13PRKAA2GHSR | |
| SCHEMBL21035497 | 0.79 | KCNH2 (0.43) | MMP1MMP9MMP13GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019104011-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2019-05-31 | — | — | WO | disclosed |