Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.40 |
| ▸ | NPC1 | O15118 | 10/20 | 0.40 |
| ▸ | RAB9A | P51151 | 10/20 | 0.40 |
| ▸ | GAA | P10253 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 8/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12196880 | 0.76 | ALDH1A1 (0.49) | ALDH1A1KDM4ENPC1RAB9AGAA | |
| SCHEMBL23502136 | 0.74 | SCN10A (0.62) | SCN10AALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL12196893 | 0.70 | ALDH1A1 (0.53) | ALDH1A1KDM4ENPC1RAB9AGAA | |
| SCHEMBL21937449 | 0.70 | MCHR1 (0.60) | SCN10AALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL22220699 | 0.68 | SCN10A (0.42) | SCN10AALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL23841231 | 0.67 | SSTR4 (0.34) | ALDH1A1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL798511 | 0.66 | MCHR1 (0.45) | SCN10AALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL2624378 | 0.66 | RAB9A (0.49) | ALDH1A1KDM4ENPC1RAB9AGAA | |
| SCHEMBL16346664 | 0.65 | ALDH1A1 (0.49) | ALDH1A1KDM4ENPC1RAB9AGAA | |
| SCHEMBL12880443 | 0.65 | APP (0.46) | SCN10AALDH1A1KDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10806733-B2 | Substituted benzaldehyde compounds and methods for their use in increasing tissue oxygenation | GLOBAL BLOOD THERAPEUTICS, INC. (US) | 2020-10-20 | — | — | US | disclosed |
| US-20190160060-A1 | SUBSTITUTED BENZALDEHYDE COMPOUNDS AND METHODS FOR THEIR USE IN INCREASING TISSUE OXYGENATION | GLOBAL BLOOD THERAPEUTICS, INC. | 2019-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10806733-B2 | Substituted benzaldehyde compounds and methods for their use in increasing tissue oxygenation | HBB, HBG2, MB | SCN10A 2229/4885ALDH1A1 216/4885KDM4E 863/4885 |
| US-20190160060-A1 | SUBSTITUTED BENZALDEHYDE COMPOUNDS AND METHODS FOR THEIR USE IN INCREASING TISSUE OXYGENATION | HBB, HBG2, MB | SCN10A 2229/4885ALDH1A1 216/4885KDM4E 863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.