Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.41 |
| ▸ | PTP4A2 | Q12974 | 1/20 | 0.41 |
| ▸ | PTP4A1 | Q93096 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | IDE | P14735 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27853457 | 0.82 | ALDH1A1 (0.50) | ALDH1A1PTP4A3PTP4A2PTP4A1MAPT | |
| SCHEMBL21037252 | 0.82 | ALDH1A1 (0.50) | ALDH1A1PTP4A3PTP4A2PTP4A1MAPT | |
| SCHEMBL22138282 | 0.79 | MEN1 (0.32) | ALDH1A1MEN1KMT2A | |
| SCHEMBL5441460 | 0.79 | ADORA2A (0.40) | ALDH1A1MAPTLMNAKDM4EMEN1 | |
| SCHEMBL5441461 | 0.79 | ADORA2A (0.40) | ALDH1A1MAPTLMNAKDM4EMEN1 | |
| SCHEMBL24089780 | 0.77 | ALDH1A1 (0.47) | ALDH1A1PTP4A3PTP4A2PTP4A1MAPT | |
| SCHEMBL21160731 | 0.77 | CYP2C9 (0.33) | ALDH1A1MEN1KMT2ACYP2C9 | |
| SCHEMBL667301 | 0.76 | ALDH1A1 (0.46) | ALDH1A1PTP4A3PTP4A2PTP4A1MAPT | |
| SCHEMBL11653026 | 0.76 | ALDH1A1 (0.46) | ALDH1A1PTP4A3PTP4A2PTP4A1MAPT | |
| SCHEMBL21234916 | 0.74 | ALDH1A1 (0.48) | ALDH1A1PTP4A3PTP4A2PTP4A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11365203-B2 | Fluorescent dye and preparation method and use thereof | FLUORESCENCE DIAGNOSIS (SHANGHAI) BIOTECH COMPANY LTD. (CN) | 2022-06-21 | — | — | US | disclosed |
| US-11209437-B2 | Fluorescent probe and preparation method and use thereof | FLUORESCENCE DIAGNOSIS (SHANGHAI) BIOTECH COMPANY (CN) | 2021-12-28 | — | — | US | disclosed |
| US-20210382060-A1 | FLUORESCENT PROBE AND PREPARATION METHOD AND USE THEREOF | Shanghai Glory Capital Management Ltd. (CN) | 2021-12-09 | — | — | US | disclosed |
| US-20200248069-A1 | FLUORESCENT PROBE, PREPARATION METHOD THEREFOR AND USE THEREOF | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2020-08-06 | — | — | US | disclosed |
| US-20190241584-A1 | FLUORESCENT DYE AND PREPARATION METHOD AND USE THEREOF | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2019-08-08 | — | — | US | disclosed |
| US-20190187144-A1 | FLUORESCENT PROBE AND PREPARATION METHOD AND USE THEREOF | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2019-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190187144-A1 | FLUORESCENT PROBE AND PREPARATION METHOD AND USE THEREOF | HNRNPF, HNRNPUL2, RAB5IF | ALDH1A1 3152/4885PTP4A3 2338/4885PTP4A2 2374/4885 |
| US-20200248069-A1 | FLUORESCENT PROBE, PREPARATION METHOD THEREFOR AND USE THEREOF | WASF2, FAM162A, HASPIN | ALDH1A1 3475/4885PTP4A3 4045/4885PTP4A2 3546/4885 |
| US-20190241584-A1 | FLUORESCENT DYE AND PREPARATION METHOD AND USE THEREOF | DNASE1, POLRMT, DCLRE1B | ALDH1A1 422/4885PTP4A3 4023/4885PTP4A2 4025/4885 |
| US-11209437-B2 | Fluorescent probe and preparation method and use thereof | HNRNPF, HNRNPUL2, RAB5IF | ALDH1A1 3152/4885PTP4A3 2338/4885PTP4A2 2374/4885 |
| US-11365203-B2 | Fluorescent dye and preparation method and use thereof | DNASE1, POLRMT, DCLRE1B | ALDH1A1 422/4885PTP4A3 4023/4885PTP4A2 4025/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.