Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27294800 | 0.73 | ALDH1A1 (0.36) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL868741 | 0.69 | ADRA2A (0.39) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL12325577 | 0.68 | — | — | |
| SCHEMBL5027292 | 0.68 | — | — | |
| SCHEMBL5027289 | 0.68 | — | — | |
| SCHEMBL4346261 | 0.67 | FDPS (0.34) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL19361696 | 0.67 | FDPS (0.34) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL23920300 | 0.67 | — | — | |
| Acrylic Acid SCHEMBL9061273 | 0.66 | LMNA (0.46) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL14268029 | 0.65 | CYP1A2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3713927-B1 | PYRIDINONE DERIVATIVES AND THEIR USE AS SELECTIVE ALK-2 INHIBITORS | NOVARTIS AG (CH) | 2021-12-15 | — | — | EP | disclosed |
| WO-2019102256-A1 | PYRIDINONE DERIVATIVES AND THEIR USE AS SELECTIVE ALK-2 INHIBITORS | NOVARTIS AG (CH) | 2019-05-31 | — | — | WO | disclosed |