Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 15/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | USP1 | O94782 | 1/20 | 0.38 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22001377 | 0.88 | CHRM1 (0.58) | CHRM1DRD2DRD4DRD3NOTUM | |
| SCHEMBL16593312 | 0.82 | CHRM1 (0.56) | CHRM1DRD2DRD4DRD3NOTUM | |
| SCHEMBL16628324 | 0.78 | CHRM1 (0.68) | CHRM1 | |
| SCHEMBL21043463 | 0.76 | MET (0.40) | CHRM1KDM4EALDH1A1 | |
| SCHEMBL21043089 | 0.75 | CHRM1 (0.75) | CHRM1 | |
| SCHEMBL1666188 | 0.74 | CHRM1 (0.74) | CHRM1DRD2DRD4DRD3USP1 | |
| SCHEMBL16593341 | 0.73 | CHRM1 (0.73) | CHRM1KDM4E | |
| SCHEMBL22001279 | 0.72 | CHRM1 (0.46) | CHRM1DRD2DRD4DRD3NOTUM | |
| SCHEMBL21042783 | 0.72 | ALDH1A1 (0.64) | CHRM1ALDH1A1 | |
| SCHEMBL1668388 | 0.71 | CHRM1 (0.61) | CHRM1KDM4EALDH1A1USP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489237-A1 | 4-AZAINDOLE DERIVATIVES | Eisai R&D Management Co., Ltd. (JP) | 2019-05-29 | — | — | EP | disclosed |