Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 12/20 | 0.46 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | USP1 | O94782 | 2/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16593538 | 0.83 | CHRM1 (0.44) | CHRM1DCTPP1DRD2DRD4DRD3 | |
| SCHEMBL22001377 | 0.83 | CHRM1 (0.58) | CHRM1ALDH1A1KDM4EMAPK1HTT | |
| SCHEMBL16593250 | 0.76 | DCTPP1 (0.44) | CHRM1DCTPP1ALDH1A1KDM4EMAPK1 | |
| SCHEMBL21043141 | 0.72 | CHRM1 (0.53) | CHRM1DCTPP1ALDH1A1KDM4EMAPK1 | |
| SCHEMBL16593242 | 0.72 | CHRM1 (0.78) | CHRM1 | |
| SCHEMBL21043119 | 0.70 | ALDH1A1 (0.42) | CHRM1ALDH1A1KDM4EHTTSMN1; SMN2 | |
| SCHEMBL21043473 | 0.69 | ALDH1A1 (0.56) | ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL21043133 | 0.69 | SMN1; SMN2 (0.50) | CHRM1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL16628324 | 0.69 | CHRM1 (0.68) | CHRM1 | |
| SCHEMBL21042784 | 0.68 | ALDH1A1 (0.52) | ALDH1A1KDM4EHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489237-B1 | 4-AZAINDOLE DERIVATIVES | EISAI R&D MAN CO LTD (JP) | 2020-05-13 | — | — | EP | disclosed |