Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | SERPINE1 | P05121 | 3/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | BCR | P11274 | 1/20 | 0.35 |
| ▸ | PRCP | P42785 | 3/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22001746 | 0.89 | ALDH1A1 (0.44) | METRXRAGRIN1GRIN2BSERPINE1 | |
| SCHEMBL21043141 | 0.76 | CHRM1 (0.53) | CHRM1ALDH1A1KDM4E | |
| SCHEMBL28467279 | 0.71 | ALDH1A1 (0.68) | SERPINE1ALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL21042783 | 0.71 | ALDH1A1 (0.64) | CHRM1ALDH1A1MAPTHTTSMN1; SMN2 | |
| SCHEMBL22001176 | 0.69 | ALDH1A1 (0.48) | CHRM1ALDH1A1MAPTHTTSMN1; SMN2 | |
| SCHEMBL28525408 | 0.69 | ALDH1A1 (0.60) | SERPINE1ALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL16593359 | 0.69 | CHRM1 (0.80) | CHRM1 | |
| SCHEMBL21043133 | 0.69 | SMN1; SMN2 (0.50) | CHRM1ALDH1A1NPC1GAAMAPT | |
| SCHEMBL21490267 | 0.68 | HTT (0.64) | ALDH1A1TSHRHTTSMN1; SMN2 | |
| SCHEMBL21043055 | 0.67 | CYP19A1 (0.45) | CHRM1ALDH1A1KDM4ENPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489237-A1 | 4-AZAINDOLE DERIVATIVES | Eisai R&D Management Co., Ltd. (JP) | 2019-05-29 | — | — | EP | disclosed |