Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.52 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.52 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 2/20 | 0.42 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.42 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15539858 | 0.92 | SSTR5 (0.55) | KCNH2SSTR5PARP15PARP10PARP2 | |
| SCHEMBL15539042 | 0.84 | SSTR5 (0.48) | KCNH2SSTR5HTR4 | |
| SCHEMBL15538422 | 0.83 | GPR119 (0.51) | KCNH2SSTR5 | |
| SCHEMBL16758044 | 0.82 | SSTR5 (0.51) | KCNH2SSTR5PARP15PARP10 | |
| SCHEMBL15540075 | 0.82 | SSTR5 (0.51) | KCNH2SSTR5 | |
| SCHEMBL15539517 | 0.81 | DRD2 (0.46) | KCNH2SSTR5 | |
| SCHEMBL15537615 | 0.81 | SSTR5 (0.55) | KCNH2SSTR5PARP15PARP10PARP2 | |
| SCHEMBL15539114 | 0.80 | SSTR5 (0.47) | KCNH2SSTR5SIGMAR1 | |
| SCHEMBL15539161 | 0.80 | RARA (0.54) | KCNH2SSTR5PARP15PARP10 | |
| SCHEMBL18818377 | 0.79 | ACHE (0.44) | KCNH2SSTR5HTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3074384-B1 | AMIDE DERIVATIVES FOR GPR119 AGONIST | CHONG KUN DANG PHARMACEUTICAL CORP (KR) | 2019-05-22 | — | — | EP | disclosed |