Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21043825 | 0.92 | CYP19A1 (0.54) | CYP19A1POLBLMNATP53MAPT | |
| SCHEMBL21043867 | 0.90 | POLB (0.59) | CYP19A1POLBLMNATP53MAPT | |
| SCHEMBL21043783 | 0.89 | GALR3 (0.44) | CYP19A1POLBLMNATP53RXFP1 | |
| SCHEMBL21043855 | 0.89 | MAPT (0.52) | CYP19A1POLBLMNATP53MAPT | |
| SCHEMBL21043849 | 0.88 | MEN1 (0.49) | CYP19A1POLBLMNATP53MAPT | |
| SCHEMBL21043878 | 0.88 | CYP19A1 (0.48) | CYP19A1POLBLMNATP53MAPT | |
| SCHEMBL21043777 | 0.88 | LMNA (0.50) | POLBLMNATP53MAPTTHRB | |
| SCHEMBL21043782 | 0.86 | CYP19A1 (0.52) | CYP19A1POLBLMNAMAPTTHRB | |
| SCHEMBL21043838 | 0.83 | TP53 (0.47) | POLBLMNATP53MAPTTHRB | |
| SCHEMBL21043806 | 0.83 | CYP19A1 (0.52) | CYP19A1POLBLMNATP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3256447-B1 | 2-OXO-3,4-DIHYDROQUINOLINE COMPOUNDS AS PLANT GROWTH REGULATORS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-06-05 | — | — | EP | disclosed |