Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | THRB | P10828 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | FGB | P02675 | 1/20 | 0.52 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.52 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21043777 | 0.89 | LMNA (0.50) | MAPTTHRBALDH1A1MEN1RECQL | |
| SCHEMBL21043855 | 0.86 | MAPT (0.52) | CYP19A1MAPTTHRBALDH1A1MEN1 | |
| SCHEMBL21043782 | 0.85 | CYP19A1 (0.52) | CYP19A1MAPTTHRBALDH1A1MEN1 | |
| SCHEMBL21043867 | 0.85 | POLB (0.59) | CYP19A1MAPTTHRBPOLBTP53 | |
| SCHEMBL21043849 | 0.85 | MEN1 (0.49) | CYP19A1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL21043878 | 0.85 | CYP19A1 (0.48) | CYP19A1MAPTTHRBALDH1A1KMT2A | |
| SCHEMBL21043791 | 0.83 | NPY5R (0.44) | POLBNPY5RTP53LMNAHTR7 | |
| SCHEMBL21043784 | 0.83 | CYP19A1 (0.52) | CYP19A1MAPTTHRBPOLBTP53 | |
| SCHEMBL21043838 | 0.83 | TP53 (0.47) | MAPTTHRBALDH1A1RECQLPOLB | |
| SCHEMBL21043801 | 0.82 | POLB (0.45) | MAPTPOLBTP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3256447-B1 | 2-OXO-3,4-DIHYDROQUINOLINE COMPOUNDS AS PLANT GROWTH REGULATORS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-06-05 | — | — | EP | disclosed |