Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29612169 | 1.00 | MAPT (0.53) | MAPTPOLBGAAADORA1MAPK14 | |
| SCHEMBL10691843 | 0.83 | MAPT (0.65) | MAPTPOLBGAAADORA1LMNA | |
| SCHEMBL30410518 | 0.79 | KEAP1 (0.50) | MAPTPOLBGAAMEN1USP2 | |
| SCHEMBL951409 | 0.79 | KEAP1 (0.50) | MAPTPOLBGAAMEN1USP2 | |
| SCHEMBL1790829 | 0.78 | MAPT (0.49) | MAPTPOLBGAAMEN1USP2 | |
| SCHEMBL11638597 | 0.78 | MAPT (0.49) | MAPTPOLBGAAMAPK14MEN1 | |
| Hydrochloric Acid SCHEMBL11626269 | 0.78 | KEAP1 (0.48) | MAPTPOLBGAAMEN1USP2 | |
| SCHEMBL25197720 | 0.77 | MAPT (0.49) | MAPTPOLBGAAADORA1LMNA | |
| SCHEMBL9749155 | 0.77 | ABCB11 (0.51) | MAPTGAAADORA1LMNA | |
| SCHEMBL15792959 | 0.77 | MAPT (0.56) | MAPTPOLBGAAADORA1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3492452-B1 | PRODUCTION METHOD FOR PYRAZOLE-AMIDE COMPOUND | JAPAN TOBACCO INC (JP) | 2022-08-31 | — | — | EP | disclosed |
| US-10981877-B2 | Production method for pyrazole-amide compound | JAPAN TOBACCO INC. (JP) | 2021-04-20 | — | — | US | disclosed |
| US-10981877-B2 | Production method for pyrazole-amide compound | JAPAN TOBACCO INC. (JP) | 2021-04-20 | — | — | US | disclosed |
| EP-3492452-A1 | PRODUCTION METHOD FOR PYRAZOLE-AMIDE COMPOUND | Japan Tobacco, Inc. (JP) | 2019-06-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10981877-B2 | Production method for pyrazole-amide compound | AADAC, NAT1, SIRT3 | MAPT 623/4885POLB 2581/4885GAA 1547/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.