Sugi Predict

Sugi Predict / Compounds / SCHEMBL951409

SCHEMBL951409

SCHEMBL951409

Nc1c(Br)cc(F)cc1C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KEAP1 Q14145 1/20 0.50
▸ KDM4E B2RXH2 3/20 0.41
▸ GLA P06280 1/20 0.41
▸ CA1 P00915 2/20 0.39
▸ CA2 P00918 2/20 0.39
▸ CA9 Q16790 2/20 0.39
▸ CA12 O43570 1/20 0.39
▸ CA3 P07451 1/20 0.39
▸ CA4 P22748 1/20 0.39
▸ CA6 P23280 1/20 0.39
▸ CA5A P35218 1/20 0.39
▸ CA7 P43166 1/20 0.39
▸ CA13 Q8N1Q1 1/20 0.39
▸ CA14 Q9ULX7 1/20 0.39
▸ CA5B Q9Y2D0 1/20 0.39
▸ AKR1C4 P17516 1/20 0.38
▸ AKR1C3 P42330 1/20 0.38
▸ AKR1C2 P52895 1/20 0.38
▸ AKR1C1 Q04828 1/20 0.38
▸ MAPT P10636 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30410518 1.00 KEAP1 (0.50) KEAP1KDM4EGLACA1CA2
Hydrochloric Acid SCHEMBL11626269 0.98 KEAP1 (0.48) KEAP1KDM4EGLACA1CA2
SCHEMBL17651538 0.85 KEAP1 (0.59) KEAP1KDM4EGLAMAPTGAA
SCHEMBL30783596 0.84 DGAT1 (0.44) KEAP1CA1CA2CA9MAPT
SCHEMBL11626266 0.82 GSK3B (0.36) KEAP1CA1CA2CA9CA3
SCHEMBL10595723 0.82 GSK3B (0.36) KEAP1CA1CA2CA9CA3
SCHEMBL951441 0.79 AKR1C3 (0.61) KDM4EGLACA1CA2CA9
SCHEMBL30690387 0.79 AKR1C3 (0.61) KDM4EGLACA1CA2CA9
SCHEMBL1888280 0.79 KEAP1 (0.59) KEAP1KDM4EGLAMAPTGAA
SCHEMBL19971600 0.79 KEAP1 (0.44) KEAP1KDM4EGLACA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260138956-A1 NOVEL COMPOUNDS AND USES THEREOF RECURSION PHARMACEUTICALS INC (US) 2026-05-21 — — US disclosed
WO-2026089784-A2 COMPOUNDS AND COMPOSITIONS FOR CONJUGATION TO BIOLIGANDS FOR IMAGING AND RADIOPHARMACEUTICAL APPLICATIONS THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2026-04-30 — — WO disclosed
EP-4731626-A1 PI3K INHIBITORS AND USE THEREOF Regor Pharmaceuticals, Inc. (US) 2026-04-29 — — EP disclosed
US-20260015341-A1 PI3K INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF HINOVA PHARMACEUTICALS INC (CN) 2026-01-15 — — US disclosed
EP-4646271-A1 SUBSTITUTED SPIROCYCLIC-PYRROLOQUINAZOLINONES AND SPIROCYCLIC-PIPERIDINOQUINAZOLINONES Mirati Therapeutics, Inc. (US) 2025-11-12 — — EP disclosed
US-20250263394-A1 COMPOUNDS, PREPARATION METHODS AND USES THEREOF INVENTISBIO LLC 2025-08-21 — — US disclosed
EP-4594318-A1 AKT1 MODULATORS Alterome Therapeutics, Inc. (US) 2025-08-06 — — EP disclosed
US-20250171452-A1 TRYPTANTHRIN DERIVATIVES AND USES THEREOF VISCIENT BIO, INC. 2025-05-29 — — US disclosed
WO-2025106644-A1 HETEROCYCLIC COMPOUNDS AS INHIBITORS OF ALPHA-V BETA-1 INTEGRIN MORPHIC THERAPEUTIC, INC. (US) 2025-05-22 — — WO disclosed
EP-4553075-A1 PI3K INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF Hinova Pharmaceuticals Inc. (CN) 2025-05-14 — — EP disclosed
US-20080261968-A1 Heterobicyclic metalloprotease inhibitors GEGE CHRISTIAN 2008-10-23 — — US disclosed
CN-101287721-A Hydrazide compound and pesticidal use of the same SUMITOMO CHEMICAL CO (JP) 2008-10-15 — — CN disclosed
WO-2008079988-A2 QUINAZOLINES FOR PDK1 INHIBITION NOVARTIS AG (CH) 2008-07-03 — — WO disclosed
EP-1937664-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME Sumitomo Chemical Company, Limited (JP) 2008-07-02 — — EP disclosed
WO-2007117607-A9 QUINAZOLINES FOR PDK1 INHIBITION NOVARTIS VACCINES & DIAGNOSTIC (US) 2008-03-06 — — WO disclosed
WO-2007117607-A2 QUINAZOLINES FOR PDK1 INHIBITION NOVARTIS AG (CH) 2007-10-18 — — WO disclosed
WO-2007043677-A9 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL CO (JP) 2007-06-07 — — WO disclosed
WO-2007043677-A9 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL CO (JP) 2007-06-07 — — WO disclosed
WO-2007043677-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-04-19 — — WO disclosed
WO-2007043677-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-04-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260138956-A1 NOVEL COMPOUNDS AND USES THEREOF SLC10A1, NR3C2, CYP2C8 KEAP1 710/4885KDM4E 4053/4885GLA 699/4885
US-20250263394-A1 COMPOUNDS, PREPARATION METHODS AND USES THEREOF PIK3CD, PIK3CA, PIK3C2B KEAP1 827/4885KDM4E 1844/4885GLA 2962/4885
US-20260015341-A1 PI3K INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF PIK3CA, PIK3R4, PIK3R1 KEAP1 2266/4885KDM4E 1342/4885GLA 3686/4885
US-20250171452-A1 TRYPTANTHRIN DERIVATIVES AND USES THEREOF IDO2, IDO1, TPSB2 KEAP1 1338/4885KDM4E 1128/4885GLA 1215/4885
US-20080261968-A1 Heterobicyclic metalloprotease inhibitors MMP13, TIMP3, MMP3 KEAP1 4354/4885KDM4E 1572/4885GLA 701/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.