Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CCR4 | P51679 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 8/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21048922 | 0.91 | EPHX2 (0.36) | KDM4EHPGDALDH1A1GAAMAPT | |
| SCHEMBL1230894 | 0.69 | CYP2C9 (0.44) | KDM4EHPGDALDH1A1MAPTPTGS1 | |
| SCHEMBL21048873 | 0.69 | JAK2 (0.46) | KDM4EALDH1A1GAAMEN1KMT2A | |
| SCHEMBL21048923 | 0.68 | PTK2 (0.49) | ALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL5310632 | 0.67 | CA12 (0.48) | HPGDNAMPTCA12CA1CA2 | |
| SCHEMBL23562359 | 0.64 | SLC22A12 (0.45) | KDM4EHPGDALDH1A1GAAMAPT | |
| SCHEMBL12445431 | 0.64 | BRAF (0.46) | CCR4BRAF | |
| SCHEMBL3267704 | 0.64 | SMN1; SMN2 (0.44) | KDM4EHPGDGAAMAPTBRD4 | |
| SCHEMBL20483300 | 0.64 | ADORA2A (0.46) | GAAMAPTKMT2ANPC1RAB9A | |
| SCHEMBL15145602 | 0.63 | MTNR1A (0.45) | KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3143021-B1 | PYRAZOLOPYRIDINES AND PYRAZOLOPYRIMIDINES | PFIZER (US) | 2019-06-12 | — | — | EP | disclosed |