Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 3/20 | 0.57 |
| ▸ | FDPS | P14324 | 6/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.42 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.42 |
| ▸ | LAP3 | P28838 | 1/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8682289 | 0.94 | SMPD1 (0.66) | SMPD1FDPSPTPN1LPAR3LPAR1 | |
| SCHEMBL2514364 | 0.92 | SMPD1 (0.69) | SMPD1FDPSPTPN1LPAR3LPAR1 | |
| SCHEMBL2370055 | 0.92 | SMPD1 (0.69) | SMPD1FDPSPTPN1LPAR3LPAR1 | |
| SCHEMBL28470942 | 0.92 | SMPD1 (0.69) | SMPD1FDPSPTPN1LPAR3LPAR1 | |
| SCHEMBL11619477 | 0.92 | SMPD1 (0.69) | SMPD1FDPSPTPN1LPAR3LPAR1 | |
| Ammonia Solution, Strong SCHEMBL28408668 | 0.90 | SMPD1 (0.67) | SMPD1FDPSPTPN1LPAR3LPAR1 | |
| SCHEMBL28701575 | 0.90 | SMPD1 (0.67) | SMPD1FDPSPTPN1LPAR3LPAR1 | |
| SCHEMBL2676632 | 0.86 | SMPD1 (0.50) | SMPD1FDPSPTPN1LPAR3LPAR1 | |
| SCHEMBL8609842 | 0.84 | FDPS (0.46) | SMPD1FDPSPTPN1LAP3 | |
| SCHEMBL28114269 | 0.82 | SMPD1 (0.57) | SMPD1PTPN1LPAR3LPAR1LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116297412-A | Method for detecting glycerol content in reconstituted tobacco of heated cigarettes | 湖北中烟工业有限责任公司 | 2023-06-23 | — | — | CN | claimed |
| CN-116297412-A | Method for detecting glycerol content in reconstituted tobacco of heated cigarettes | 湖北中烟工业有限责任公司 | 2023-06-23 | — | — | CN | disclosed |
| WO-2015026566-A1 | LUBRICANT HAVING IMPROVED ANTIWEAR PROPERTIES | ICL-IP AMERICA INC. (US) | 2015-02-26 | — | — | WO | disclosed |
| US-8895582-B2 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INC. (US) | 2014-11-25 | — | — | US | disclosed |
| US-8759374-B2 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INC. (US) | 2014-06-24 | — | — | US | disclosed |
| US-20130053348-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | QIAN XIANGPING (US) | 2013-02-28 | — | — | US | disclosed |
| US-20120135964-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | QIAN XIANGPING (US) | 2012-05-31 | — | — | US | disclosed |
| US-8088793-B2 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INC. (US) | 2012-01-03 | — | — | US | disclosed |
| EP-2195328-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Cytokinetics, Incorporated (US) | 2010-06-16 | — | — | EP | disclosed |
| US-20090275537-A1 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INC. | 2009-11-05 | — | — | US | disclosed |
| WO-2009023193-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2009-02-19 | — | — | WO | disclosed |
| EP-0758369-A4 | SYNTHETIC ESTER LUBRICANT HAVING IMPROVED ANTIWEAR PROPERTIES | FMC CORP (US) | 1998-10-21 | — | — | EP | disclosed |
| EP-0758369-A1 | SYNTHETIC ESTER LUBRICANT HAVING IMPROVED ANTIWEAR PROPERTIES | FMC CORPORATION (US) | 1997-02-19 | — | — | EP | disclosed |
| US-5560849-A | CONTAINING ARYL DIPHOSPHATE ESTER; HIGH TEMPERATURE LUBRICANT | FMC CORPORATION (US) | 1996-10-01 | — | — | US | disclosed |
| WO-1996020263-A1 | SYNTHETIC ESTER LUBRICANT HAVING IMPROVED ANTIWEAR PROPERTIES | FMC CORPORATION (US) | 1996-07-04 | — | — | WO | disclosed |
| EP-0671625-A1 | A process for detecting biomolecules by means of an enzymatic amplification system | MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) | 1995-09-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275537-A1 | Certain chemical entities, compositions, and methods | MYLK, MYH2, MYH10 | SMPD1 235/4885FDPS 3701/4885PTPN1 606/4885 |
| US-20120135964-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | MYLK, MYH2, MYH10 | SMPD1 235/4885FDPS 3701/4885PTPN1 606/4885 |
| US-20130053348-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | MYLK, MYH2, MYH10 | SMPD1 235/4885FDPS 3701/4885PTPN1 606/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.