Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14645332 | 0.86 | HSP90AB1 (0.42) | HSP90AB1HTTHSD17B10TSHRKAT2B | |
| SCHEMBL7072235 | 0.84 | TSHR (0.40) | HTTHSD17B10TSHRKAT2BALDH1A1 | |
| SCHEMBL350771 | 0.83 | SMN1; SMN2 (0.42) | HTTTSHRKAT2BALDH1A1EGFR | |
| SCHEMBL14646005 | 0.80 | MAPT (0.46) | HSP90AB1HTTHSD17B10ALDH1A1KDM4E | |
| SCHEMBL19268668 | 0.79 | CYP3A4 (0.40) | LMNAMAPTL3MBTL1 | |
| SCHEMBL14645328 | 0.79 | HSP90AB1 (0.37) | HSP90AB1HTTHSD17B10ALDH1A1KDM4E | |
| SCHEMBL365715 | 0.77 | AKR1B1 (0.38) | HTTHSD17B10ALDH1A1MAPTKMT2A | |
| SCHEMBL15695235 | 0.77 | MAPT (0.46) | HSP90AB1HTTHSD17B10ALDH1A1KDM4E | |
| SCHEMBL14645396 | 0.77 | HPGD (0.40) | HSP90AB1HTTHSD17B10ALDH1A1KDM4E | |
| SCHEMBL15695223 | 0.76 | MAPT (0.35) | HSP90AB1HTTHSD17B10ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11713371-B2 | Polar functional group-partially introduced polymer, preparation method therefor, and organic electronic element containing same | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2023-08-01 | — | — | US | disclosed |
| US-11713371-B2 | Polar functional group-partially introduced polymer, preparation method therefor, and organic electronic element containing same | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2023-08-01 | — | — | US | disclosed |
| US-11713371-B2 | Polar functional group-partially introduced polymer, preparation method therefor, and organic electronic element containing same | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2023-08-01 | — | — | US | disclosed |
| US-20220267300-A1 | SULFONAMIDE DERIVATIVES AND USES THEREOF | NodThera Limited (GB) | 2022-08-25 | — | — | US | disclosed |
| CN-114761383-A | Sulfonamide derivatives and uses thereof | 诺瑟拉有限公司 | 2022-07-15 | — | — | CN | disclosed |
| EP-3983388-A1 | SULFONAMIDE DERIVATIVES AND USES THEREOF | Nodthera Limited (GB) | 2022-04-20 | — | — | EP | disclosed |
| WO-2020249669-A1 | SULFONAMIDE DERIVATIVES AND USES THEREOF | NodThera Limited (GB) | 2020-12-17 | — | — | WO | disclosed |
| WO-2020249669-A1 | SULFONAMIDE DERIVATIVES AND USES THEREOF | NodThera Limited (GB) | 2020-12-17 | — | — | WO | disclosed |
| US-20200308342-A1 | POLAR FUNCTIONAL GROUP-PARTIALLY INTRODUCED POLYMER, PREPARATION METHOD THEREFOR, AND ORGANIC ELECTRONIC ELEMENT CONTAINING SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2020-10-01 | — | — | US | disclosed |
| WO-2019112220-A1 | POLAR FUNCTIONAL GROUP-PARTIALLY INTRODUCED POLYMER, PREPARATION METHOD THEREFOR, AND ORGANIC ELECTRONIC ELEMENT CONTAINING SAME | 한국화학연구원 | 2019-06-13 | — | — | WO | disclosed |
| WO-2019112220-A1 | POLAR FUNCTIONAL GROUP-PARTIALLY INTRODUCED POLYMER, PREPARATION METHOD THEREFOR, AND ORGANIC ELECTRONIC ELEMENT CONTAINING SAME | 한국화학연구원 | 2019-06-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220267300-A1 | SULFONAMIDE DERIVATIVES AND USES THEREOF | IL1B, IL1A, CASP1 | HSP90AB1 1336/4885HTT 4669/4885HSD17B10 2145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.