SCHEMBL21054690

SCHEMBL21054690

FC(F)(F)[C@@H](Cl)C=C(Cl)Cl

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21055009 1.00 ALDH1A1 (0.33) ALDH1A1HSD17B10
SCHEMBL31062680 0.80 ALDH1A1 (0.32) ALDH1A1HSD17B10
SCHEMBL31062689 0.77 ALDH1A1 (0.33) ALDH1A1HSD17B10
SCHEMBL19945959 0.73 LMNA (0.32)
Hydrochloric Acid SCHEMBL28497283 0.71 LMNA (0.30)
SCHEMBL31458761 0.70
SCHEMBL31458653 0.70
SCHEMBL9537595 0.69 TSHR (0.30)
SCHEMBL11344705 0.69 TSHR (0.30)
SCHEMBL9164111 0.69 TSHR (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3720834-A1 PROCESS AND INTERMEDIATES FOR PREPARING 1,1,3-TRICHLORO-4,4,4-TRIFLUOROBUT-1-ENE AND (E)-1,1,1,4,4,4-HEXAFLUOROBUT-2-ENE The Chemours Company FC, LLC (US) 2020-10-14 EP disclosed
WO-2019113052-A1 PROCESS AND INTERMEDIATES FOR PREPARING 1,1,3-TRICHLORO-4,4,4-TRIFLUOROBUT-1-ENE AND (E)-1,1,1,4,4,4-HEXAFLUOROBUT-2-ENE THE CHEMOURS COMPANY FC, LLC (US) 2019-06-13 WO disclosed