SCHEMBL21055009

SCHEMBL21055009

FC(F)(F)C(Cl)C=C(Cl)Cl

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21054690 1.00 ALDH1A1 (0.33) ALDH1A1HSD17B10
SCHEMBL31062680 0.80 ALDH1A1 (0.32) ALDH1A1HSD17B10
SCHEMBL31062689 0.77 ALDH1A1 (0.33) ALDH1A1HSD17B10
SCHEMBL19945959 0.73 LMNA (0.32)
Hydrochloric Acid SCHEMBL28497283 0.71 LMNA (0.30)
SCHEMBL31458761 0.70
SCHEMBL31458653 0.70
SCHEMBL9537595 0.69 TSHR (0.30)
SCHEMBL11344705 0.69 TSHR (0.30)
SCHEMBL9164111 0.69 TSHR (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025019752-A2 HCL RECOVERY IN FLUOROCHEMICAL PROCESSES TO PRODUCE HIGH QUALITY ANHYDROUS HCL OR AQUEOUS HCL OF SPECIFIC CONCENTRATION THE CHEMOURS COMPANY FC, LLC (US) 2025-01-23 WO claimed
WO-2024222187-A1 HIGH SPECIFIC SURFACE AREA CHROMIUM-BASED CATALYST WITH BORON-BASED PORES AND METHOD FOR PREPARING HIGH RATIO OF Z-FLUORINE-CONTAINING OLEFIN/E-FLUORINE-CONTAINING OLEFIN 泉州宇极新材料科技有限公司 2024-10-31 WO claimed
US-11390574-B2 Process for producing 1,1,3-trichloro-4,4,4-trifluorobut-1-ene THE CHEMOURS COMPANY FC, LLC (US) 2022-07-19 US claimed
US-20210188743-A1 Process and Intermediates for Preparing (E)-1,1,1,4,4,4-hexafluorobut-2-ene THE CHEMOURS COMPANY FC, LLC (US) 2021-06-24 US claimed
EP-3720834-A1 PROCESS AND INTERMEDIATES FOR PREPARING 1,1,3-TRICHLORO-4,4,4-TRIFLUOROBUT-1-ENE AND (E)-1,1,1,4,4,4-HEXAFLUOROBUT-2-ENE The Chemours Company FC, LLC (US) 2020-10-14 EP claimed
CN-111433177-A Processes and intermediates for the preparation of 1,1, 3-trichloro-4, 4, 4-trifluorobut-1-ene and (E) -1,1,1,4,4, 4-hexafluorobut-2-ene 科慕埃弗西有限公司 2020-07-17 CN claimed
WO-2019113052-A1 PROCESS AND INTERMEDIATES FOR PREPARING 1,1,3-TRICHLORO-4,4,4-TRIFLUOROBUT-1-ENE AND (E)-1,1,1,4,4,4-HEXAFLUOROBUT-2-ENE THE CHEMOURS COMPANY FC, LLC (US) 2019-06-13 WO claimed
EP-4665812-A1 COMPOSITIONS COMPRISING HEXAFLUOROBUTENE, TETRAFLUOROPROPENE, AND TETRAFLUOROETHANE AND USES THEREOF The Chemours Company FC, LLC (US) 2025-12-24 EP disclosed
EP-4658632-A1 CO-PRODUCTION OF 1,1,1-TRIFLUOROPROPENE (1243ZF) AND E-1,1,1,4,4,4-HEXAFLUORO-2-BUTENE (E-1336MZZ) The Chemours Company FC, LLC (US) 2025-12-10 EP disclosed
WO-2025019752-A2 HCL RECOVERY IN FLUOROCHEMICAL PROCESSES TO PRODUCE HIGH QUALITY ANHYDROUS HCL OR AQUEOUS HCL OF SPECIFIC CONCENTRATION THE CHEMOURS COMPANY FC, LLC (US) 2025-01-23 WO disclosed
WO-2024222187-A1 HIGH SPECIFIC SURFACE AREA CHROMIUM-BASED CATALYST WITH BORON-BASED PORES AND METHOD FOR PREPARING HIGH RATIO OF Z-FLUORINE-CONTAINING OLEFIN/E-FLUORINE-CONTAINING OLEFIN 泉州宇极新材料科技有限公司 2024-10-31 WO disclosed
WO-2024173623-A1 COMPOSITIONS COMPRISING HEXAFLUOROBUTENE, TETRAFLUOROPROPENE, AND TETRAFLUOROETHANE AND USES THEREOF THE CHEMOURS COMPANY FC, LLC (US) 2024-08-22 WO disclosed
WO-2024163379-A1 CO-PRODUCTION OF 1,1,1-TRIFLUOROPROPENE (1243ZF) AND E-1,1,1,4,4,4-HEXAFLUORO-2-BUTENE (E-1336MZZ) THE CHEMOURS COMPANY FC, LLC (US) 2024-08-08 WO disclosed
US-20210188743-A1 Process and Intermediates for Preparing (E)-1,1,1,4,4,4-hexafluorobut-2-ene THE CHEMOURS COMPANY FC, LLC (US) 2021-06-24 US disclosed
EP-3720834-A1 PROCESS AND INTERMEDIATES FOR PREPARING 1,1,3-TRICHLORO-4,4,4-TRIFLUOROBUT-1-ENE AND (E)-1,1,1,4,4,4-HEXAFLUOROBUT-2-ENE The Chemours Company FC, LLC (US) 2020-10-14 EP disclosed
EP-3720834-A1 PROCESS AND INTERMEDIATES FOR PREPARING 1,1,3-TRICHLORO-4,4,4-TRIFLUOROBUT-1-ENE AND (E)-1,1,1,4,4,4-HEXAFLUOROBUT-2-ENE The Chemours Company FC, LLC (US) 2020-10-14 EP disclosed
CN-111433177-A Processes and intermediates for the preparation of 1,1, 3-trichloro-4, 4, 4-trifluorobut-1-ene and (E) -1,1,1,4,4, 4-hexafluorobut-2-ene 科慕埃弗西有限公司 2020-07-17 CN disclosed
CN-111433177-A Processes and intermediates for the preparation of 1,1, 3-trichloro-4, 4, 4-trifluorobut-1-ene and (E) -1,1,1,4,4, 4-hexafluorobut-2-ene 科慕埃弗西有限公司 2020-07-17 CN disclosed
WO-2019113052-A1 PROCESS AND INTERMEDIATES FOR PREPARING 1,1,3-TRICHLORO-4,4,4-TRIFLUOROBUT-1-ENE AND (E)-1,1,1,4,4,4-HEXAFLUOROBUT-2-ENE THE CHEMOURS COMPANY FC, LLC (US) 2019-06-13 WO disclosed
WO-2019113052-A1 PROCESS AND INTERMEDIATES FOR PREPARING 1,1,3-TRICHLORO-4,4,4-TRIFLUOROBUT-1-ENE AND (E)-1,1,1,4,4,4-HEXAFLUOROBUT-2-ENE THE CHEMOURS COMPANY FC, LLC (US) 2019-06-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210188743-A1 Process and Intermediates for Preparing (E)-1,1,1,4,4,4-hexafluorobut-2-ene FRG1, PFN1, TOE1 ALDH1A1 2452/4885HSD17B10 3350/4885
US-11390574-B2 Process for producing 1,1,3-trichloro-4,4,4-trifluorobut-1-ene PFN1, TOE1, FRG1 ALDH1A1 1927/4885HSD17B10 2883/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.