Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | GPR3 | P46089 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | BCR | P11274 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21055994 | 1.00 | ACHE (0.38) | ACHECYP2C19CYP2C9CYP3A4GPR3 | |
| SCHEMBL8933405 | 0.76 | KEAP1 (0.41) | ACHECYP1A2CYP2A6ALDH1A1TDP1 | |
| SCHEMBL21480791 | 0.75 | CYP1A2 (0.48) | ACHECYP2C19CYP2C9CYP3A4GPR3 | |
| SCHEMBL1723322 | 0.73 | ACHE (0.52) | ACHECYP2C19CYP2C9CYP3A4CYP1A2 | |
| SCHEMBL12736406 | 0.73 | ACHE (0.65) | ACHESMN1; SMN2GAAALDH1A1MAPT | |
| SCHEMBL31010991 | 0.73 | ACHE (0.39) | ACHECYP2A6SMN1; SMN2GAAALDH1A1 | |
| SCHEMBL31038383 | 0.72 | CA1 (0.41) | ACHESMN1; SMN2GAAALDH1A1MAPT | |
| SCHEMBL23068615 | 0.72 | NPC1 (0.33) | CYP2C19CYP2C9CYP1A2SMN1; SMN2GAA | |
| SCHEMBL21055991 | 0.72 | AGPAT2 (0.38) | ALDH1A1MAPTTDP1KMT2ATSHR | |
| SCHEMBL21055982 | 0.72 | NPC1 (0.33) | CYP2C19CYP2C9CYP1A2SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11434253-B2 | Enantiopure terphenyls with two ortho-atropisomeric axes | UNIVERSITE DE STRASBOURG (FR) | 2022-09-06 | — | — | US | disclosed |
| US-20210070785-A1 | ENANTIOPURE TERPHENYLS WITH TWO ORTHO-ATROPISOMERIC AXES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2021-03-11 | — | — | US | disclosed |
| EP-3498684-B1 | ENANTIOPURE TERPHENYLS WITH TWO ORTHO-ATROPISOMERIC AXES | UNIV STRASBOURG (FR) | 2020-10-14 | — | — | EP | disclosed |
| EP-3498684-A1 | ENANTIOPURE TERPHENYLS WITH TWO ORTHO-ATROPISOMERIC AXES | Université de Strasbourg (FR) | 2019-06-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11434253-B2 | Enantiopure terphenyls with two ortho-atropisomeric axes | THOP1, COMT, TPR | ACHE 22/4885CYP2C19 64/4885CYP2C9 67/4885 |
| US-20210070785-A1 | ENANTIOPURE TERPHENYLS WITH TWO ORTHO-ATROPISOMERIC AXES | THOP1, COMT, TPR | ACHE 22/4885CYP2C19 64/4885CYP2C9 67/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.