Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 4/20 | 0.70 |
| ▸ | P2RX2 | Q9UBL9 | 4/20 | 0.70 |
| ▸ | NT5E | P21589 | 3/20 | 0.68 |
| ▸ | TP53 | P04637 | 2/20 | 0.66 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.66 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.66 |
| ▸ | MITF | O75030 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | DNPH1 | O43598 | 2/20 | 0.64 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.63 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.61 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.61 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.61 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.61 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.58 |
| ▸ | SRC | P12931 | 1/20 | 0.55 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4058981 | 0.90 | DNPH1 (0.77) | P2RX3P2RX2NT5ETP53PAX8 | |
| SCHEMBL21058279 | 0.85 | P2RX3 (0.76) | P2RX3P2RX2NT5EADORA3DNPH1 | |
| SCHEMBL21058282 | 0.84 | P2RX3 (0.88) | P2RX3P2RX2NT5ESMN1; SMN2SLC29A1 | |
| SCHEMBL13033867 | 0.83 | P2RX3 (0.98) | P2RX3P2RX2NT5ETP53ADORA3 | |
| SCHEMBL4319955 | 0.83 | P2RX3 (0.98) | P2RX3P2RX2NT5ETP53ADORA3 | |
| SCHEMBL30076630 | 0.83 | P2RX3 (0.98) | P2RX3P2RX2NT5ETP53ADORA3 | |
| SCHEMBL29941330 | 0.83 | P2RX3 (0.98) | P2RX3P2RX2NT5ETP53ADORA3 | |
| SCHEMBL9607782 | 0.83 | P2RX3 (0.98) | P2RX3P2RX2NT5ETP53ADORA3 | |
| SCHEMBL15794372 | 0.83 | P2RX3 (1.00) | P2RX3P2RX2NT5ETP53ADORA3 | |
| SCHEMBL14178287 | 0.83 | P2RX3 (1.00) | P2RX3P2RX2NT5ETP53ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190185906-A1 | IN SITU VISUALIZATION OF KINASE ACTIVITY | DANA-FARBER CANCER INSTITUTE, INC. | 2019-06-20 | — | — | US | claimed |
| US-20190185906-A1 | IN SITU VISUALIZATION OF KINASE ACTIVITY | DANA-FARBER CANCER INSTITUTE, INC. | 2019-06-20 | — | — | US | disclosed |