Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNPH1 | O43598 | 7/20 | 0.77 |
| ▸ | TP53 | P04637 | 2/20 | 0.75 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.75 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.75 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.75 |
| ▸ | MITF | O75030 | 1/20 | 0.75 |
| ▸ | LMNA | P02545 | 1/20 | 0.75 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.67 |
| ▸ | P2RX2 | Q9UBL9 | 3/20 | 0.67 |
| ▸ | NT5E | P21589 | 2/20 | 0.66 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.65 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.64 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.64 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.62 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.62 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.62 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.62 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.62 |
| ▸ | LDHA | P00338 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21058281 | 0.90 | P2RX3 (0.70) | DNPH1TP53PAX8SMN1; SMN2ADORA3 | |
| SCHEMBL218999 | 0.87 | DNPH1 (1.00) | DNPH1TP53ADORA3SLC29A1P2RX3 | |
| SCHEMBL17022278 | 0.87 | DNPH1 (1.00) | DNPH1TP53ADORA3SLC29A1P2RX3 | |
| SCHEMBL13957724 | 0.87 | DNPH1 (1.00) | DNPH1TP53ADORA3SLC29A1P2RX3 | |
| SCHEMBL29564113 | 0.87 | DNPH1 (1.00) | DNPH1TP53ADORA3SLC29A1P2RX3 | |
| SCHEMBL23440101 | 0.87 | DNPH1 (1.00) | DNPH1TP53ADORA3SLC29A1P2RX3 | |
| SCHEMBL13972003 | 0.87 | DNPH1 (1.00) | DNPH1TP53ADORA3SLC29A1P2RX3 | |
| SCHEMBL14700471 | 0.87 | DNPH1 (1.00) | DNPH1TP53ADORA3SLC29A1P2RX3 | |
| SCHEMBL32662533 | 0.87 | ADORA3 (0.75) | DNPH1TP53PAX8SMN1; SMN2ADORA3 | |
| Kinetin Riboside SCHEMBL217034 | 0.86 | ADORA3 (1.00) | TP53PAX8SMN1; SMN2ADORA3SLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0355825-A2 | Viral treatment system | Prendergast, Patrick T. (IE) | 1990-02-28 | — | — | EP | claimed |
| US-20120196825-A1 | COMPOSITIONS AND METHODS FOR MODULATING THE IMMUNE SYSTEM | SUPPORTIVE THERAPEUTICS AG (CH) | 2012-08-02 | — | — | US | disclosed |
| US-20090156546-A1 | Compositions and methods for modulating the immune system | SUPPORTIVE THERAPEUTICS AG (CH) | 2009-06-18 | — | — | US | disclosed |
| EP-2026810-A2 | COMPOSITIONS AND METHODS FOR MODULATING THE IMMUNE SYSTEM | Prendergast, Patrick T. (AU) | 2009-02-25 | — | — | EP | disclosed |
| WO-2007131973-A2 | COMPOSITIONS AND METHODS FOR MODULATING THE IMMUNE SYSTEM | PRENDERGAST PATRICK T (AU) | 2007-11-22 | — | — | WO | disclosed |
| EP-0355825-A2 | Viral treatment system | Prendergast, Patrick T. (IE) | 1990-02-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156546-A1 | Compositions and methods for modulating the immune system | MRE11, XPA, MPL | DNPH1 1551/4885TP53 201/4885PAX8 1325/4885 |
| US-20120196825-A1 | COMPOSITIONS AND METHODS FOR MODULATING THE IMMUNE SYSTEM | MRE11, XPA, MPL | DNPH1 1551/4885TP53 201/4885PAX8 1325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.