Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KMO | O15229 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22758020 | 0.84 | KDM4E (0.39) | KDM4ELMNASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL14797918 | 0.83 | HSD11B1 (0.41) | KDM4ELMNASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL14797917 | 0.83 | HSD11B1 (0.41) | KDM4ELMNASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL13471772 | 0.83 | ALOX15 (0.38) | KDM4ELMNASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL20381712 | 0.75 | KDM4E (0.38) | KDM4ELMNASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL29743263 | 0.70 | KDM4E (0.50) | KDM4ELMNASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL21058367 | 0.68 | KDM4E (0.40) | KDM4ELMNASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL21098997 | 0.68 | KDM4E (0.44) | KDM4ELMNASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL16566770 | 0.67 | KDM4E (0.47) | KDM4ELMNASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL51027 | 0.67 | TSHR (0.65) | KDM4ELMNASMN1; SMN2HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190185415-A1 | BRANCHED 3-PHENYLPROPIONIC ACID DERIVATIVES AND THEIR USE | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2019-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190185415-A1 | BRANCHED 3-PHENYLPROPIONIC ACID DERIVATIVES AND THEIR USE | PC, FABP3, PCCA | KDM4E 4051/4885LMNA 195/4885SMN1; SMN2 2527/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.