SCHEMBL21058380

SCHEMBL21058380

CCCC(=O)N[C@H]1C(OCc2ccccc2)O[C@H](COC(=O)CCC(=O)O)[C@@H](OC(=O)CCC(=O)O)[C@@H]1OCc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.48
▸ TLR4 O00206 5/20 0.47
▸ POLB P06746 1/20 0.45
▸ KMT2A Q03164 1/20 0.44
▸ SSTR3 P32745 5/20 0.44
▸ SSTR5 P35346 5/20 0.44
▸ SSTR2 P30874 3/20 0.44
▸ SSTR1 P30872 1/20 0.44
▸ SSTR4 P31391 1/20 0.44
▸ TNF P01375 1/20 0.41
▸ MCHR1 Q99705 6/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31352990 0.95 LMNA (0.50) LMNATLR4POLBKMT2ASSTR3
SCHEMBL21058359 0.93 LMNA (0.48) LMNATLR4POLBKMT2ASSTR3
SCHEMBL21058370 0.92 LMNA (0.50) LMNAPOLBKMT2ASSTR3SSTR5
SCHEMBL21058369 0.90 SSTR5 (0.54) SSTR3SSTR5SSTR2SSTR1SSTR4
SCHEMBL21058372 0.86 LMNA (0.65) LMNAPOLBKMT2ASSTR3SSTR5
SCHEMBL21058361 0.84 LMNA (0.44) LMNAPOLBKMT2ASSTR3SSTR5
SCHEMBL21058356 0.82 HTT (0.48) LMNAPOLBKMT2ASSTR3SSTR5
SCHEMBL21058383 0.81 SSTR5 (0.53) SSTR3SSTR5SSTR2SSTR1SSTR4
SCHEMBL21058366 0.81 SSTR3 (0.47) LMNASSTR3SSTR5SSTR2SSTR1
SCHEMBL21058342 0.81 SSTR3 (0.48) LMNATLR4SSTR3SSTR5SSTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12552823-B2 Glucosamine derivatives and pharmaceutical uses thereof Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2026-02-17 — — US disclosed
US-20250353870-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF RISEN SUZHOU PHARMA TECH CO LTD (CN) 2025-11-20 — — US disclosed
US-12312378-B2 Glucosamine derivatives for the prevention or treatment of joint disorders Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2025-05-27 — — US disclosed
US-20240051982-A1 GLUCOSAMINE DERIVATIVES FOR THE PREVENTION OR TREATMENT OF JOINT DISORDERS Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2024-02-15 — — US disclosed
US-11718636-B2 Glucosamine derivatives for the prevention or treatment of joint disorders Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2023-08-08 — — US disclosed
US-20230227488-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF RISEN SUZHOU PHARMA TECH CO LTD (CN) 2023-07-20 — — US disclosed
US-11591358-B2 Glucosamine derivatives and pharmaceutical uses thereof Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2023-02-28 — — US disclosed
CN-115594724-A Glucosamine derivatives for preventing or treating joint diseases 润佳(苏州)医药科技有限公司(CN) 2023-01-13 — — CN disclosed
CN-111971290-B Glucosamine derivatives for preventing or treating joint diseases 润佳(苏州)医药科技有限公司 2022-10-14 — — CN disclosed
US-20210079033-A1 GLUCOSAMINE DERIVATIVES FOR THE PREVENTION OR TREATMENT OF JOINT DISORDERS Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2021-03-18 — — US disclosed
US-20190185502-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF RISEN (SUZHOU) PHARMA TECH CO, LTD. (CN) 2019-06-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250353870-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF OGT, UGGT1, GLA LMNA 2743/4885TLR4 896/4885POLB 3798/4885
US-20210079033-A1 GLUCOSAMINE DERIVATIVES FOR THE PREVENTION OR TREATMENT OF JOINT DISORDERS OGT, UGGT1, GLA LMNA 2632/4885TLR4 660/4885POLB 4305/4885
US-20240051982-A1 GLUCOSAMINE DERIVATIVES FOR THE PREVENTION OR TREATMENT OF JOINT DISORDERS OGT, UGGT1, FUT6 LMNA 3002/4885TLR4 858/4885POLB 4253/4885
US-11718636-B2 Glucosamine derivatives for the prevention or treatment of joint disorders OGT, UGGT1, GLA LMNA 2632/4885TLR4 660/4885POLB 4305/4885
US-12552823-B2 Glucosamine derivatives and pharmaceutical uses thereof SOST, FUT6, SLC5A1 LMNA 992/4885TLR4 201/4885POLB 2918/4885
US-20230227488-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF OGT, UGGT1, GLA LMNA 2743/4885TLR4 896/4885POLB 3798/4885
US-20190185502-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF OGT, UGGT1, GLA LMNA 2743/4885TLR4 896/4885POLB 3798/4885
US-11591358-B2 Glucosamine derivatives and pharmaceutical uses thereof OGT, UGGT1, GLA LMNA 2743/4885TLR4 896/4885POLB 3798/4885
US-12312378-B2 Glucosamine derivatives for the prevention or treatment of joint disorders OGT, UGGT1, FUT6 LMNA 3002/4885TLR4 858/4885POLB 4253/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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