Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.85 |
| ▸ | TSHR | P16473 | 1/20 | 0.85 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.85 |
| ▸ | PKM | P14618 | 3/20 | 0.47 |
| ▸ | HCAR3 | P49019 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GALR3 | O60755 | 1/20 | 0.43 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30100543 | 0.99 | ALDH1A1 (0.83) | ALDH1A1TSHRTDP1PKMHCAR3 | |
| Hydrochloric Acid SCHEMBL454521 | 0.99 | ALDH1A1 (0.83) | ALDH1A1TSHRTDP1PKMHCAR3 | |
| SCHEMBL28924912 | 0.94 | ALDH1A1 (0.78) | ALDH1A1TSHRTDP1PKMHCAR3 | |
| SCHEMBL8653764 | 0.93 | ALDH1A1 (0.73) | ALDH1A1TSHRTDP1PKMHCAR3 | |
| SCHEMBL8658868 | 0.93 | ALDH1A1 (0.73) | ALDH1A1TSHRTDP1PKMHCAR3 | |
| SCHEMBL29829407 | 0.92 | ALDH1A1 (1.00) | ALDH1A1TSHRTDP1PKMHCAR3 | |
| SCHEMBL109266 | 0.92 | ALDH1A1 (1.00) | ALDH1A1TSHRTDP1PKMHCAR3 | |
| Hydrochloric Acid SCHEMBL8641009 | 0.92 | ALDH1A1 (0.72) | ALDH1A1TSHRTDP1PKMHCAR3 | |
| Hydrochloric Acid SCHEMBL8643503 | 0.92 | ALDH1A1 (0.72) | ALDH1A1TSHRTDP1PKMHCAR3 | |
| SCHEMBL8799830 | 0.91 | ALDH1A1 (0.88) | ALDH1A1TSHRTDP1PKMHCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 501 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016026710-A1 | COSMETIC COMPOSITION FOR KERATIN FIBRES | ALFA PARF GROUP S.P.A. (IT) | 2016-02-25 | — | — | WO | claimed |
| EP-2158942-A2 | Direct hair dye composition comprising insoluble oxygenated compounds and processes | L'Oreal (FR) | 2010-03-03 | — | — | EP | claimed |
| US-7651534-B2 | Direct dye composition comprising at least one insoluble oxygenated compound, and processes using this composition | L'OREAL SA (FR) | 2010-01-26 | — | — | US | claimed |
| EP-1757326-B1 | Direct dying composition comprising insoluble oxygenated compounds and processes | OREAL (FR) | 2009-01-07 | — | — | EP | claimed |
| US-20070044251-A1 | Direct dye composition comprising at least one insoluble oxygenated compound, and processes using this composition | L'OREAL S.A. (FR) | 2007-03-01 | — | — | US | claimed |
| EP-1757326-A1 | Direct dying composition comprising insoluble oxygenated compounds and processes | L'Oréal (FR) | 2007-02-28 | — | — | EP | claimed |
| EP-1328244-B1 | AGENT AND METHOD FOR COLOURING KERATIN FIBRES | WELLA AG (DE) | 2006-10-11 | — | — | EP | claimed |
| EP-0898954-B1 | Composition for dyeing keratin fibres | WELLA AG (DE) | 2004-09-15 | — | — | EP | claimed |
| US-6773463-B2 | A MIXTURE OF A 4-NITRO-2,1,3-BENZOXADIAZOLE, A 4-NITRO-2,1,3-BENZOTHIADIAZOLE, OR A 4-NITRO-2,1,3-BENZO-SELENADIAZOLE AND AT LEAST ONE AMINE, PHENOL, OR AMINONITROBENZENE; INTENSE COLORATIONS; MILD CONDITIONS; DIRECT HAIR DYE | WELLA AKTIENGESELLSCHAFT (DE) | 2004-08-10 | — | — | US | claimed |
| EP-1430876-A1 | Composition containing a direct dyestuff and a specific polymer for colouring of keratinic fibres, method for the preparation thereof and process of dyeing with such a composition | L'OREAL (FR) | 2004-06-23 | — | — | EP | claimed |
| EP-0601302-B1 | Hair dyeing composition containing 3-pyridinazo dyes and novel 3-pyridazo dyes | WELLA AG (DE) | 1996-07-10 | — | — | EP | claimed |
| EP-0608393-B1 | HAIR DYES | WELLA AG (DE) | 1996-03-20 | — | — | EP | claimed |
| EP-0600045-B1 | HAIR DYE | WELLA AG (DE) | 1996-01-24 | — | — | EP | claimed |
| US-5409502-A | Acid resistance | WELLA AKTIENGESELLSCHAFT (DE) | 1995-04-25 | — | — | US | claimed |
| EP-0601302-A1 | Hair dyeing composition containing 3-pyridinazo dyes and novel 3-pyridazo dyes | Wella Aktiengesellschaft (DE) | 1994-06-15 | — | — | EP | claimed |
| EP-0480829-B1 | Hair dyeing composition containing anthraquinones | OREAL (FR) | 1994-04-06 | — | — | EP | claimed |
| US-5226924-A | 1,4-DI(MONO- OR POLY) HYDROXYALKYLAMINO-9,10-ANTHRAQUINONES FOR DYEING HUMAN KERATINOUS FIBRES, COSMETIC COMPOSITION CONTAINING THEM IN COMBINATION WITH AZO AND NITROBENZENE DYES, AND HAIR-DYEING PROCESS USING THEM | L'OREAL (FR) | 1993-07-13 | — | — | US | claimed |
| EP-0460127-B1 | HAIR TONING AGENT IN FOAM FORM | Wella Aktiengesellschaft (DE) | 1993-01-20 | — | — | EP | claimed |
| US-5132461-A | Process for the production of 4-[ethyl-(2'-hydroxyethyl)-amino]-1-[(2'-hydroxyethyl)-amino]-2-nitro-benzene | WELLA AKTIENGESELLSCHAFT (DE) | 1992-07-21 | — | — | US | claimed |
| US-4900869-A | Process for the production of 4-[ethyl-(2'-hydroxyethyl)-amino]-1-[(2'-hydroxyethyl)-amino]-2-nitrobenzene | Wella, Aktiengesellschaft (DE) | 1990-02-13 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070044251-A1 | Direct dye composition comprising at least one insoluble oxygenated compound, and processes using this composition | KRT18, DSG1, PLOD2 | ALDH1A1 188/4885TSHR 4670/4885TDP1 1969/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.