Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA known ✓ | P10253 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.83 |
| ▸ | TSHR | P16473 | 1/20 | 0.83 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.83 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GALR3 | O60755 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL454521 | 1.00 | ALDH1A1 (0.83) | ALDH1A1TSHRTDP1PKMHCAR3 | |
| SCHEMBL210589 | 0.99 | ALDH1A1 (0.85) | ALDH1A1TSHRTDP1PKMHCAR3 | |
| Hydrochloric Acid SCHEMBL8643503 | 0.93 | ALDH1A1 (0.72) | ALDH1A1TSHRTDP1PKMHCAR3 | |
| Hydrochloric Acid SCHEMBL8641009 | 0.93 | ALDH1A1 (0.72) | ALDH1A1TSHRTDP1PKMHCAR3 | |
| SCHEMBL28924912 | 0.92 | ALDH1A1 (0.78) | ALDH1A1TSHRTDP1PKMHCAR3 | |
| SCHEMBL8653764 | 0.92 | ALDH1A1 (0.73) | ALDH1A1TSHRTDP1PKMHCAR3 | |
| Hydrochloric Acid SCHEMBL8974864 | 0.92 | ALDH1A1 (0.86) | ALDH1A1TSHRTDP1PKMHCAR3 | |
| SCHEMBL8658868 | 0.92 | ALDH1A1 (0.73) | ALDH1A1TSHRTDP1PKMHCAR3 | |
| SCHEMBL109266 | 0.91 | ALDH1A1 (1.00) | ALDH1A1TSHRTDP1PKMHCAR3 | |
| SCHEMBL29829407 | 0.91 | ALDH1A1 (1.00) | ALDH1A1TSHRTDP1PKMHCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4637352-A2 | ANTIMICROBIAL COMBINATIONS | CLARIANT INTERNATIONAL LTD (CH) | 2025-10-29 | — | — | EP | disclosed |
| EP-4598500-A1 | COMBINATION COMPRISING A GLUCAMIDE AND A CO-EMULSIFIER | CLARIANT INTERNATIONAL LTD (CH) | 2025-08-13 | — | — | EP | disclosed |
| WO-2025108737-A1 | COSMETIC COMPOSITIONS COMPRISING A POLYMER AND A SURFACTANT | CLARIANT INTERNATIONAL LTD (CH) | 2025-05-30 | — | — | WO | disclosed |
| EP-4557953-A1 | ANTIMICROBIAL COMBINATIONS | CLARIANT INTERNATIONAL LTD (CH) | 2025-05-28 | — | — | EP | disclosed |
| CN-119997925-A | Combinations comprising glucamide and co-emulsifiers | 科莱恩国际有限公司 | 2025-05-13 | — | — | CN | disclosed |
| EP-3735827-B1 | COMPOSITION FOR INHIBITING MICRO-ORGANISMS | CLARIANT INT LTD (CH) | 2025-04-09 | — | — | EP | disclosed |
| CN-119584861-A | Antimicrobial combinations | 科莱恩国际有限公司 | 2025-03-07 | — | — | CN | disclosed |
| WO-2025003367-A1 | VITAMIN COMPOSITION FOR USE IN COSMETIC FORMULATIONS | CLARIANT INTERNATIONAL LTD (CH) | 2025-01-02 | — | — | WO | disclosed |
| EP-4441111-A1 | WATER-SOLUBLE AND/OR WATER-SWELLABLE HYBRID POLYMER | CLARIANT INTERNATIONAL LTD (CH) | 2024-10-09 | — | — | EP | disclosed |
| CN-118556090-A | Water-soluble and/or water-swellable hybrid polymers | 科莱恩国际有限公司 | 2024-08-27 | — | — | CN | disclosed |
| EP-4363401-A1 | BIO-BASED ISETHIONATE COMPOUNDS | Clariant International Ltd (CH) | 2024-05-08 | — | — | EP | disclosed |
| WO-2024074409-A1 | COMBINATION COMPRISING A GLUCAMIDE AND A CO-EMULSIFIER | CLARIANT INTERNATIONAL LTD (CH) | 2024-04-11 | — | — | WO | disclosed |
| WO-2024074693-A1 | BIO-BASED ANTIMICROBIAL COMPOUNDS | CLARIANT INTERNATIONAL LTD (CH) | 2024-04-11 | — | — | WO | disclosed |
| EP-3229918-B1 | COMPOSITION AND PROCEDURE FOR TREATING KERATINIC FIBERS WITH FLASH EVAPORATION | HENKEL AG & CO KGAA (DE) | 2024-03-13 | — | — | EP | disclosed |
| WO-2023247803-A2 | ANTIMICROBIAL COMBINATIONS | CLARIANT INTERNATIONAL LTD (CH) | 2023-12-28 | — | — | WO | disclosed |
| WO-2023227802-A1 | ANTIMICROBIAL COMBINATIONS | CLARIANT INTERNATIONAL LTD (CH) | 2023-11-30 | — | — | WO | disclosed |
| CN-110300573-B | Use of biobased polymers in cosmetic, dermatological or pharmaceutical compositions | 科莱恩国际有限公司 | 2023-07-25 | — | — | CN | disclosed |
| WO-2023099681-A1 | WATER-SOLUBLE AND/OR WATER-SWELLABLE HYBRID POLYMER | CLARIANT INTERNATIONAL LTD (CH) | 2023-06-08 | — | — | WO | disclosed |
| WO-2023274887-A1 | BIO-BASED ISETHIONATE COMPOUNDS | CLARIANT INTERNATIONAL LTD (CH) | 2023-01-05 | — | — | WO | disclosed |