Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21060838 | 0.83 | MAPT (0.63) | ALDH1A1MAPTCRBNSMN1; SMN2TSHR | |
| SCHEMBL21060836 | 0.83 | PTGS2 (0.41) | ALDH1A1MAPTPTGS2PTGS1MMP2 | |
| SCHEMBL28881751 | 0.79 | MAPT (0.71) | ALDH1A1MAPTCRBNPTGS2PTGS1 | |
| SCHEMBL644453 | 0.73 | HTR2A (0.51) | ALDH1A1MAPTPTGS2TRPA1MMP2 | |
| SCHEMBL10884103 | 0.72 | PSEN1 (0.48) | ALDH1A1MAPTCRBNMMP2MMP9 | |
| SCHEMBL16877035 | 0.71 | ALDH1A1 (0.45) | ALDH1A1MAPTPTGS2PTGS1MMP2 | |
| SCHEMBL16877034 | 0.71 | ALDH1A1 (0.45) | ALDH1A1MAPTPTGS2PTGS1MMP2 | |
| SCHEMBL3105251 | 0.70 | MMP2 (0.65) | ALDH1A1MAPTTRPA1MMP2SMN1; SMN2 | |
| SCHEMBL643581 | 0.70 | HTR2A (0.49) | MAPTPTGS2PTGS1TRPA1MMP2 | |
| SCHEMBL3240288 | 0.70 | HTR2A (0.49) | ALDH1A1PTGS2PTGS1TRPA1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11884839-B2 | Acetal-protected silanol group-containing polysiloxane composition | NISSAN CHEMICAL CORPORATION (JP) | 2024-01-30 | — | — | US | disclosed |
| CN-109563371-B | Polysiloxane composition comprising acetal-protected silanol groups | 日产化学株式会社 | 2021-09-21 | — | — | CN | disclosed |
| US-20190185707-A1 | ACETAL-PROTECTED SILANOL GROUP-CONTAINING POLYSILOXANE COMPOSITION | NISSAN CHEMICAL CORPORATION (JP) | 2019-06-20 | — | — | US | disclosed |