Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 4/20 | 0.37 |
| ▸ | CNR1 | P21554 | 3/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.34 |
| ▸ | GALK1 | P51570 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | RAF1 | P04049 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21060908 | 0.80 | ALOX15 (0.44) | ALOX15MAPTALDH1A1 | |
| SCHEMBL21061011 | 0.80 | ALOX15 (0.44) | ALOX15MAPTALDH1A1 | |
| SCHEMBL21060890 | 0.80 | ALOX15 (0.44) | ALOX15MAPTALDH1A1 | |
| SCHEMBL21061105 | 0.78 | CNR2 (0.39) | ALOX15KDM4EMAPTTP53CYP3A4 | |
| SCHEMBL21061091 | 0.77 | GPR84 (0.47) | MAPTGALK1GPR84 | |
| SCHEMBL21060896 | 0.77 | GPR84 (0.47) | MAPTGALK1GPR84 | |
| SCHEMBL21061162 | 0.77 | GPR84 (0.47) | MAPTGALK1GPR84 | |
| SCHEMBL21061015 | 0.77 | GPR84 (0.47) | MAPTGALK1GPR84 | |
| SCHEMBL21061026 | 0.76 | GPR84 (0.34) | ALOX15KDM4EMAPTTP53CYP3A4 | |
| SCHEMBL3029318 | 0.71 | NGFR (0.42) | ALOX15KDM4ETSHRMAPK14ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210220328-A1 | PYRROLE DERIVATIVES AS ACC INHIBITORS | ALMIRALL SA (ES) | 2021-07-22 | — | — | US | disclosed |
| CN-111886230-A | Pyrrole derivatives as ACC inhibitors | 阿尔米雷尔有限公司 | 2020-11-03 | — | — | CN | disclosed |
| EP-3724182-A1 | PYRROLE DERIVATIVES AS ACC INHIBITORS | Almirall S.A. (ES) | 2020-10-21 | — | — | EP | disclosed |
| WO-2019115405-A1 | PYRROLE DERIVATIVES AS ACC INHIBITORS | ALMIRALL, S.A. (ES) | 2019-06-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210220328-A1 | PYRROLE DERIVATIVES AS ACC INHIBITORS | ACACA, ACACB, PCCA | ALOX15 848/4885KDM4E 1463/4885MAPT 1394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.