Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | LIPE | Q05469 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12502989 | 0.84 | MEN1 (0.56) | MAPK1HPGDRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL21061056 | 0.80 | ALDH1A1 (0.48) | MAPK1GLAHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL28444437 | 0.78 | ACP3 (0.51) | RAB9ASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL22783988 | 0.77 | SMN1; SMN2 (0.53) | MAPK1HPGDRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL21137744 | 0.73 | GAA (0.39) | MAPK1GLAHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL21061058 | 0.73 | SMN1; SMN2 (0.55) | MAPK1GLAHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL18357054 | 0.72 | RAB9A (0.58) | MAPK1GLAHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL28341288 | 0.72 | PPARG (0.54) | HPGDRXFP1ALDH1A1MEN1KMT2A | |
| Acetamide SCHEMBL27527964 | 0.71 | SMN1; SMN2 (0.51) | MAPK1GLAHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL21137786 | 0.70 | RAB9A (0.56) | MAPK1HPGDRAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200392138-A1 | PESTICIDALLY ACTIVE MESOIONIC HETEROCYCLIC COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-12-17 | — | — | US | disclosed |
| US-20200392138-A1 | PESTICIDALLY ACTIVE MESOIONIC HETEROCYCLIC COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-12-17 | — | — | US | disclosed |
| CN-111511721-A | Pesticidally active mesoionic heterocyclic compounds | 先正达参股股份有限公司 | 2020-08-07 | — | — | CN | disclosed |
| WO-2019115404-A1 | PESTICIDALLY ACTIVE MESOIONIC HETEROCYCLIC COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-06-20 | — | — | WO | disclosed |
| WO-2019115404-A1 | PESTICIDALLY ACTIVE MESOIONIC HETEROCYCLIC COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-06-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200392138-A1 | PESTICIDALLY ACTIVE MESOIONIC HETEROCYCLIC COMPOUNDS | DDT, ACHE, MNS1 | MAPK1 1280/4885GLA 2721/4885HPGD 1485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.