Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | RORC | P51449 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8160960 | 1.00 | MAPT (0.43) | MAPTALDH1A1SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL2008435 | 0.80 | RORC (0.46) | MAPTALDH1A1SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL21593844 | 0.76 | ALDH1A1 (0.51) | MAPTALDH1A1SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL21062091 | 0.75 | NPC1 (0.49) | MAPTALDH1A1SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL23880807 | 0.74 | NPC1 (0.50) | MAPTALDH1A1SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL2719215 | 0.74 | RORC (0.46) | MAPTSMN1; SMN2SLC13A5L3MBTL1LMNA | |
| SCHEMBL4369405 | 0.73 | RORC (0.45) | MAPTALDH1A1SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL13680782 | 0.73 | SLC13A5 (0.49) | MAPTALDH1A1SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL5527912 | 0.73 | ACACB (0.51) | MAPTALDH1A1SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL1701348 | 0.72 | PIK3CD (0.51) | MAPTALDH1A1SMN1; SMN2KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3724280-A1 | COMPOSITIONS AND METHODS FOR HIGH-TEMPERATURE JETTING OF VISCOUS THERMOSETS TO CREATE SOLID ARTICLES VIA ADDITIVE FABRICATION | DSM IP Assets B.V. (NL) | 2020-10-21 | — | — | EP | disclosed |
| WO-2019117723-A1 | COMPOSITIONS AND METHODS FOR HIGH-TEMPERATURE JETTING OF VISCOUS THERMOSETS TO CREATE SOLID ARTICLES VIA ADDITIVE FABRICATION | DSM IP ASSETS B.V. (NL) | 2019-06-20 | — | — | WO | disclosed |