Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL21063578 | 0.80 | CHRNA7 (0.38) | IRAK4PDK1PDK2FAAHMGLL | |
| SCHEMBL21063666 | 0.75 | SMN1; SMN2 (0.34) | MGLL | |
| SCHEMBL21063652 | 0.74 | ACHE (0.49) | — | |
| SCHEMBL21063624 | 0.74 | KDM2B (0.33) | — | |
| SCHEMBL4956499 | 0.69 | HTR2C (0.48) | IRAK4 | |
| SCHEMBL22660701 | 0.69 | ACKR3 (0.44) | — | |
| SCHEMBL29098496 | 0.67 | PLAT (0.42) | IRAK4PDK1PDK2 | |
| SCHEMBL24958725 | 0.66 | PLAT (0.48) | IRAK4 | |
| SCHEMBL21063473 | 0.63 | PDK1 (0.32) | PDK1PDK2 | |
| SCHEMBL25263478 | 0.62 | HTR2A (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019118612-A1 | TARGETING COMPOUNDS | ZAFGEN, INC. (US) | 2019-06-20 | — | — | WO | disclosed |