Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.31 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL21063623 | 0.80 | KDM2B (0.40) | KDM2BKDM5A | |
| SCHEMBL21063598 | 0.75 | KDM2B (0.45) | KDM2BKDM5A | |
| SCHEMBL21063580 | 0.74 | IRAK4 (0.32) | — | |
| SCHEMBL21063652 | 0.71 | ACHE (0.49) | — | |
| SCHEMBL4735031 | 0.68 | SCD (0.32) | — | |
| SCHEMBL4737902 | 0.68 | RBP4 (0.46) | KDM5A | |
| SCHEMBL20497264 | 0.64 | KDM2B (0.52) | KDM2BKCNH2 | |
| SCHEMBL21063473 | 0.63 | PDK1 (0.32) | — | |
| SCHEMBL20497250 | 0.62 | PIM1 (0.45) | KDM2BKCNH2 | |
| SCHEMBL20497248 | 0.62 | PIM1 (0.45) | KDM2BKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019118612-A1 | TARGETING COMPOUNDS | ZAFGEN, INC. (US) | 2019-06-20 | — | — | WO | disclosed |