Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20782448 | 0.79 | CYP19A1 (0.32) | CYP19A1 | |
| SCHEMBL24121301 | 0.77 | CYP19A1 (0.35) | CYP19A1 | |
| SCHEMBL20793023 | 0.76 | — | — | |
| SCHEMBL18501682 | 0.76 | NUDT1 (0.33) | — | |
| SCHEMBL19115660 | 0.75 | CYP19A1 (0.32) | CYP19A1 | |
| SCHEMBL21191530 | 0.75 | LOXL2 (0.30) | — | |
| SCHEMBL22856619 | 0.73 | AHR (0.36) | — | |
| SCHEMBL22639173 | 0.72 | — | — | |
| SCHEMBL20656672 | 0.71 | NPC1 (0.42) | CYP19A1 | |
| SCHEMBL18574401 | 0.70 | CYP1A2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210113491-A1 | Compositions comprising Quinone and/or Quinol and methods of preparations and use thereof | TCW PT MANAGEMENT COMPANY LLC, AS COLLATERAL AGENT | 2021-04-22 | — | — | US | disclosed |
| US-10308639-B2 | Phosphatidylinositol 3-kinase inhibitors | GILEAD SCIENCES, INC. (US) | 2019-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210113491-A1 | Compositions comprising Quinone and/or Quinol and methods of preparations and use thereof | NQO1, SDHA, SDHB | CYP19A1 797/4885 |
| US-10308639-B2 | Phosphatidylinositol 3-kinase inhibitors | PIK3CA, AKT3, AKT2 | CYP19A1 694/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.