SCHEMBL21065816

SCHEMBL21065816

CC(COc1ccc(C(C)(C)c2ccc(OCC(C)OCC3CO3)cc2)cc1)COC1CO1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.55
TP53 P04637 3/20 0.55
TSHR P16473 3/20 0.55
KMT2A Q03164 3/20 0.55
HIF1A Q16665 3/20 0.55
MAPT P10636 2/20 0.55
HPGD P15428 2/20 0.55
MEN1 O00255 2/20 0.55
CYP1A2 P05177 1/20 0.55
PPARG P37231 1/20 0.55
HTT P42858 1/20 0.38
AR P10275 2/20 0.34
TDP1 Q9NUW8 1/20 0.33
PKM P14618 2/20 0.33
LMNA P02545 1/20 0.33
GAA P10253 1/20 0.33
KDM4E B2RXH2 1/20 0.31
PSMB1 P20618 1/20 0.31
PSMB5 P28074 1/20 0.31
PSMB2 P49721 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL194944 0.89 ALDH1A1 (0.68) ALDH1A1TP53TSHRKMT2AHIF1A
SCHEMBL24856805 0.87 ALDH1A1 (0.65) ALDH1A1TP53TSHRKMT2AHIF1A
SCHEMBL26703804 0.87 ALDH1A1 (0.65) ALDH1A1TP53TSHRKMT2AHIF1A
SCHEMBL27945705 0.85 ALDH1A1 (0.62) ALDH1A1TP53TSHRKMT2AHIF1A
SCHEMBL17922238 0.84 KMT2A (0.58) ALDH1A1TP53TSHRKMT2AHIF1A
SCHEMBL18373646 0.84 KMT2A (0.60) ALDH1A1TP53TSHRKMT2AHIF1A
SCHEMBL13385074 0.83 KMT2A (0.80) ALDH1A1TP53TSHRKMT2AHIF1A
SCHEMBL26645460 0.83 KMT2A (0.80) ALDH1A1TP53TSHRKMT2AHIF1A
SCHEMBL24313480 0.83 KMT2A (0.56) ALDH1A1TP53TSHRKMT2AHIF1A
SCHEMBL14626470 0.83 KMT2A (0.59) ALDH1A1TP53TSHRKMT2AHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10919918-B2 Tetracarboxylic dianhydride, polyimide resin and method for producing the same, photosensitive resin compositions, patterning process, method for forming cured film, interlayer insulating film, surface protective film, and electronic parts SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-02-16 US disclosed
US-20190169211-A1 NOVEL TETRACARBOXYLIC DIANHYDRIDE, POLYIMIDE RESIN AND METHOD FOR PRODUCING THE SAME, PHOTOSENSITIVE RESIN COMPOSITIONS, PATTERNING PROCESS, METHOD FOR FORMING CURED FILM, INTERLAYER INSULATING FILM, SURFACE PROTECTIVE FILM, AND ELECTRONIC PARTS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2019-06-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190169211-A1 NOVEL TETRACARBOXYLIC DIANHYDRIDE, POLYIMIDE RESIN AND METHOD FOR PRODUCING THE SAME, PHOTOSENSITIVE RESIN COMPOSITIONS, PATTERNING PROCESS, METHOD FOR FORMING CURED FILM, INTERLAYER INSULATING FILM, SURFACE PROTECTIVE FILM, AND ELECTRONIC PARTS CAD, LCP1, CD79B ALDH1A1 1608/4885TP53 4775/4885TSHR 3758/4885
US-10919918-B2 Tetracarboxylic dianhydride, polyimide resin and method for producing the same, photosensitive resin compositions, patterning process, method for forming cured film, interlayer insulating film, surface protective film, and electronic parts CAD, CDH1, LCP1 ALDH1A1 1147/4885TP53 4717/4885TSHR 3635/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.