Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13722893 | 1.00 | REN (0.42) | RENALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL23754645 | 0.83 | ALDH1A1 (0.45) | RENALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL2582068 | 0.82 | ALDH1A1 (0.44) | RENALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL2580428 | 0.78 | ALDH1A1 (0.41) | RENALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL563333 | 0.76 | REN (0.50) | RENALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL2568643 | 0.75 | MEN1 (0.43) | RENALDH1A1MEN1KMT2A | |
| SCHEMBL3884654 | 0.75 | MC4R (0.48) | MEN1KMT2A | |
| SCHEMBL21351575 | 0.74 | IDO1 (0.48) | RENALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL20216100 | 0.74 | TSHR (0.52) | ALDH1A1TDP1LMNA | |
| SCHEMBL27172833 | 0.74 | TSHR (0.52) | ALDH1A1TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3501546-A2 | CYSTEINE DRUG CONJUGATES AND USE OF SAME | Seattle Genetics, Inc. (US) | 2019-06-26 | — | — | EP | disclosed |