Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | REN | P00797 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23754645 | 0.82 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL2582068 | 0.81 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL2589547 | 0.80 | REN (0.48) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL21065879 | 0.78 | REN (0.42) | ALDH1A1MEN1KMT2ALMNAREN | |
| SCHEMBL13722893 | 0.78 | REN (0.42) | ALDH1A1MEN1KMT2ALMNAREN | |
| SCHEMBL2568643 | 0.74 | MEN1 (0.43) | ALDH1A1MEN1KMT2ASMN1; SMN2REN | |
| SCHEMBL3884654 | 0.74 | MC4R (0.48) | MEN1KMT2A | |
| SCHEMBL21351575 | 0.73 | IDO1 (0.48) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL12989094 | 0.70 | SMN1; SMN2 (0.41) | ALDH1A1LMNASMN1; SMN2TSHRKDM4E | |
| SCHEMBL825414 | 0.70 | LMNA (0.63) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2563847-B1 | MCR DENDRIMERS | LEIBNIZ INST FÜR PFLANZENBIOCHEMIE IPB (DE) | 2016-04-13 | — | — | EP | disclosed |
| EP-2563847-A1 | MCR DENDRIMERS | Leibniz-Institut für Pflanzenbiochemie (IPB) (DE) | 2013-03-06 | — | — | EP | disclosed |
| WO-2011134607-A1 | MCR DENDRIMERS | LEIBNIZ-INSTITUT FÜR PFLANZENBIOCHEMIE (DE) | 2011-11-03 | — | — | WO | disclosed |