Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.41 |
| ▸ | REN | P00797 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3884654 | 0.87 | MC4R (0.48) | MEN1KMT2A | |
| SCHEMBL23754645 | 0.86 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2ALMNANPSR1 | |
| SCHEMBL8327663 | 0.85 | ROCK1 (0.44) | ALDH1A1TDP1 | |
| SCHEMBL21065879 | 0.82 | REN (0.42) | ALDH1A1TDP1MEN1KMT2ALMNA | |
| SCHEMBL13722893 | 0.82 | REN (0.42) | ALDH1A1TDP1MEN1KMT2ALMNA | |
| SCHEMBL1023411 | 0.81 | CARM1 (0.55) | ALDH1A1TDP1MEN1KMT2AKDM4E | |
| SCHEMBL2580428 | 0.81 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL21351575 | 0.80 | IDO1 (0.48) | ALDH1A1TDP1MEN1KMT2AKDM4E | |
| SCHEMBL31235807 | 0.80 | CARM1 (0.46) | SMN1; SMN2CARM1PRMT6PRMT8 | |
| SCHEMBL22498765 | 0.80 | CARM1 (0.46) | SMN1; SMN2CARM1PRMT6PRMT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2563847-B1 | MCR DENDRIMERS | LEIBNIZ INST FÜR PFLANZENBIOCHEMIE IPB (DE) | 2016-04-13 | — | — | EP | disclosed |
| EP-2563847-A1 | MCR DENDRIMERS | Leibniz-Institut für Pflanzenbiochemie (IPB) (DE) | 2013-03-06 | — | — | EP | disclosed |
| WO-2011134607-A1 | MCR DENDRIMERS | LEIBNIZ-INSTITUT FÜR PFLANZENBIOCHEMIE (DE) | 2011-11-03 | — | — | WO | disclosed |