Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.72 |
| ▸ | TFEB | P19484 | 1/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.70 |
| ▸ | MAPT | P10636 | 4/20 | 0.69 |
| ▸ | NPC1 | O15118 | 3/20 | 0.69 |
| ▸ | RAB9A | P51151 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | BCHE | P06276 | 1/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.60 |
| ▸ | MAOB | P27338 | 3/20 | 0.59 |
| ▸ | AR | P10275 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.57 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30842599 | 1.00 | NFE2L2 (0.72) | NFE2L2TFEBKDM4EMAPTNPC1 | |
| SCHEMBL21067353 | 1.00 | NFE2L2 (0.72) | NFE2L2TFEBKDM4EMAPTNPC1 | |
| Coumarinic Acid Methyl Ether SCHEMBL29369917 | 0.86 | NFE2L2 (0.77) | NFE2L2TFEBKDM4EMAPTNPC1 | |
| Coumarinic Acid Methyl Ether SCHEMBL79060 | 0.86 | NFE2L2 (0.77) | NFE2L2TFEBKDM4EMAPTNPC1 | |
| Coumarinic Acid Methyl Ether SCHEMBL83064 | 0.86 | NFE2L2 (0.77) | NFE2L2TFEBKDM4EMAPTNPC1 | |
| Coumarinic Acid Methyl Ether SCHEMBL714857 | 0.86 | NFE2L2 (0.77) | NFE2L2TFEBKDM4EMAPTNPC1 | |
| SCHEMBL6844089 | 0.85 | NFE2L2 (0.74) | NFE2L2MAPTNPC1RAB9ALMNA | |
| SCHEMBL6844087 | 0.85 | NFE2L2 (0.74) | NFE2L2MAPTNPC1RAB9ALMNA | |
| Coumarinic Acid Methyl Ether SCHEMBL10437229 | 0.84 | NFE2L2 (0.74) | NFE2L2TFEBKDM4EMAPTNPC1 | |
| Coumarinic Acid Methyl Ether SCHEMBL4743620 | 0.84 | NFE2L2 (0.74) | NFE2L2TFEBKDM4EMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117902981-A | Synthesis method of (E) -4-o-methoxyphenyl-2-oxo-3-ethyl butenoate | 兴义民族师范学院 | 2024-04-19 | — | — | CN | disclosed |
| US-11446398-B2 | Regulated biocircuit systems | OBSIDIAN THERAPEUTICS, INC. (US) | 2022-09-20 | — | — | US | disclosed |
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |