Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16986622 | 0.89 | CYP1A2 (0.42) | TP53MAPTPOLBLMNAALDH1A1 | |
| SCHEMBL23752444 | 0.89 | MAPT (0.44) | TP53MAPTPOLBLMNANQO2 | |
| SCHEMBL9899341 | 0.84 | IDO1 (0.45) | MAPTLMNAALDH1A1KDM4E | |
| SCHEMBL19854691 | 0.76 | PTPRC (0.46) | TP53MAPTLMNAALDH1A1CYP1A2 | |
| SCHEMBL4997975 | 0.74 | DYRK2 (0.52) | TP53MAPTPOLBLMNANQO2 | |
| SCHEMBL11021673 | 0.71 | PGR (0.44) | TP53MAPTPOLBLMNANQO2 | |
| SCHEMBL19568178 | 0.70 | TSHR (0.50) | POLBLMNAALDH1A1MAPK1KDM4E | |
| SCHEMBL6557130 | 0.70 | TSHR (0.50) | POLBLMNAALDH1A1MAPK1KDM4E | |
| SCHEMBL19854635 | 0.69 | S100A4 (0.43) | CYP1A2MAPK1 | |
| SCHEMBL20402831 | 0.69 | DYRK2 (0.47) | TP53MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11446398-B2 | Regulated biocircuit systems | OBSIDIAN THERAPEUTICS, INC. (US) | 2022-09-20 | — | — | US | disclosed |
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |