Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | KDM4B | O94953 | 2/20 | 0.50 |
| ▸ | KDM5C | P41229 | 2/20 | 0.50 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.50 |
| ▸ | AURKA | O14965 | 1/20 | 0.50 |
| ▸ | PRKACA | P17612 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
| ▸ | KDM6B | O15054 | 1/20 | 0.50 |
| ▸ | KDM4A | O75164 | 1/20 | 0.50 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.50 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.50 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.49 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | CDK4 | P11802 | 1/20 | 0.46 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24457726 | 0.83 | CDK4 (0.54) | HSP90AA1ALDH1A1KDM4EKDM4BKDM5C | |
| SCHEMBL10719025 | 0.78 | ALDH1A1 (0.61) | ALDH1A1KDM4EMAPTHSD17B10NPC1 | |
| SCHEMBL6835805 | 0.77 | LMNA (0.47) | ALDH1A1KDM4EKDM4BKDM5CKDM5B | |
| Bromide SCHEMBL6841110 | 0.75 | LMNA (0.46) | ALDH1A1KDM4EKDM4BKDM5CKDM5B | |
| SCHEMBL30872470 | 0.74 | ALDH1A1 (0.46) | HSP90AA1ALDH1A1KDM4EKDM4BKDM5C | |
| SCHEMBL29039419 | 0.74 | HSP90AA1 (0.49) | HSP90AA1ALDH1A1KDM4EKDM4BKDM5C | |
| SCHEMBL6840084 | 0.74 | KDM4B (0.46) | ALDH1A1KDM4EKDM4BKDM5CKDM5B | |
| SCHEMBL23071629 | 0.74 | HSP90AA1 (0.63) | HSP90AA1ALDH1A1KDM4EAURKAPRKACA | |
| SCHEMBL128834 | 0.72 | CYP19A1 (0.62) | HSP90AA1ALDH1A1KDM4EKDM4BKDM5C | |
| SCHEMBL29516285 | 0.72 | CYP19A1 (0.62) | HSP90AA1ALDH1A1KDM4EKDM4BKDM5C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11446398-B2 | Regulated biocircuit systems | OBSIDIAN THERAPEUTICS, INC. (US) | 2022-09-20 | — | — | US | disclosed |
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |