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SCHEMBL21068060

SCHEMBL21068060

Nc1ncnc2c1ncn2[C@@H]1O[C@H](COS(=O)(=O)NC(=O)C(N)CS)[C@@H](O)[C@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ SARS1 P49591 1/20 0.87
▸ LARS1 Q9P2J5 2/20 0.83
▸ TARS1 P26639 2/20 0.80
▸ MARS1 P56192 1/20 0.80
▸ RARS1 P54136 1/20 0.79
▸ IARS1 P41252 1/20 0.77
▸ HARS1 P12081 1/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3187637 1.00 SARS1 (0.87) SARS1LARS1TARS1MARS1RARS1
SCHEMBL3187665 1.00 SARS1 (0.87) SARS1LARS1TARS1MARS1RARS1
SCHEMBL21067959 0.93 SARS1 (1.00) SARS1LARS1TARS1MARS1RARS1
SCHEMBL4313369 0.93 SARS1 (1.00) SARS1LARS1TARS1MARS1RARS1
SCHEMBL178824 0.92 SARS1 (0.85) SARS1LARS1TARS1MARS1RARS1
SCHEMBL178823 0.92 SARS1 (0.85) SARS1LARS1TARS1MARS1RARS1
SCHEMBL30270578 0.92 SARS1 (0.85) SARS1LARS1TARS1MARS1RARS1
SCHEMBL13773211 0.91 MARS1 (0.84) SARS1LARS1TARS1MARS1RARS1
Leusa SCHEMBL29562511 0.91 LARS1 (1.00) SARS1LARS1TARS1MARS1RARS1
SCHEMBL13773209 0.91 MARS1 (0.84) SARS1LARS1TARS1MARS1RARS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11446398-B2 Regulated biocircuit systems OBSIDIAN THERAPEUTICS, INC. (US) 2022-09-20 — — US disclosed
US-20190192691-A1 REGULATED BIOCIRCUIT SYSTEMS OBSIDIAN THERAPEUTICS, INC. 2019-06-27 — — US disclosed
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