SCHEMBL4313369

SCHEMBL4313369

Nc1ncnc2c1ncn2[C@@H]1O[C@H](COS(=O)(=O)NC(=O)[C@@H](N)CO)[C@@H](O)[C@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SARS1 P49591 3/20 1.00
LARS1 Q9P2J5 2/20 0.83
TARS1 P26639 2/20 0.80
MARS1 P56192 1/20 0.80
IARS1 P41252 1/20 0.77
RARS1 P54136 1/20 0.76
HARS1 P12081 1/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21067959 1.00 SARS1 (1.00) SARS1LARS1TARS1MARS1IARS1
SCHEMBL3187637 0.93 SARS1 (0.87) SARS1LARS1TARS1MARS1IARS1
SCHEMBL21068060 0.93 SARS1 (0.87) SARS1LARS1TARS1MARS1IARS1
SCHEMBL3187665 0.93 SARS1 (0.87) SARS1LARS1TARS1MARS1IARS1
SCHEMBL178823 0.92 SARS1 (0.85) SARS1LARS1TARS1MARS1IARS1
SCHEMBL30270578 0.92 SARS1 (0.85) SARS1LARS1TARS1MARS1IARS1
SCHEMBL178824 0.92 SARS1 (0.85) SARS1LARS1TARS1MARS1IARS1
SCHEMBL13773209 0.91 MARS1 (0.84) SARS1LARS1TARS1MARS1IARS1
Leusa SCHEMBL29562511 0.91 LARS1 (1.00) SARS1LARS1TARS1MARS1IARS1
SCHEMBL13773211 0.91 MARS1 (0.84) SARS1LARS1TARS1MARS1IARS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12582466-B2 Ablation assembly to treat target regions of tissue in organs ARGÁ MEDTECH SA (CH) 2026-03-24 US disclosed
US-12564722-B2 System and method for synchronizing energy delivery to the cardiac rhythm ANGIODYNAMICS, INC. (US) 2026-03-03 US disclosed
US-12562230-B2 Memory device with high content density and encoding method thereof MACRONIX INTERNATIONAL CO., LTD. (TW) 2026-02-24 US disclosed
EP-4688866-A1 BINDING AGENTS TARGETING TROP2-EXPRESSING TUMOR CELLS Kisoji Biotechnology Inc. (CA) 2026-02-11 EP disclosed
US-12508423-B2 Device for tissue electrotransfer using a microelectrode RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2025-12-30 US disclosed
EP-4161418-B1 ABLATION EQUIPMENT TO TREAT TARGET REGIONS OF TISSUE IN ORGANS ARGA MEDTECH SA (CH) 2025-12-24 EP disclosed
US-20250177741-A1 FOURIER ANALYSIS SPECTROSCOPY FOR MONITORING TISSUE IMPEDANCE CHANGES AND TREATMENT OUTCOME DURING ELECTROPORATION-BASED-THERAPIES ANGIODYNAMICS, INC. 2025-06-05 US disclosed
US-20250152230-A1 IMMUNOTHERAPEUTIC METHODS USING ELECTROPORATION VIRGINIA TECH INTELLECTUAL PROPERTIES INC (US) 2025-05-15 US disclosed
US-12290688-B1 System for neurostimulation signal reconstruction JOHN MICHAEL SASHA (US) 2025-05-06 US disclosed
EP-4540221-A2 A MULTIFUNCTIONAL BIOADHESIVE DESIGNED WITH CHEMICAL FUNCTIONALITY INDUCED SUTURED BIOLOGICAL BUILDING BLOCKS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-04-23 EP disclosed
US-11266839-B1 Neurostimulation using partial signal combinations JOHN MICHAEL SASHA (US) 2022-03-08 US disclosed
US-11253705-B1 Systems and methods for improved spinal cord stimulation JOHN MICHAEL SASHA (US) 2022-02-22 US disclosed
CN-114057799-A Organic electroluminescent material and device 环球展览公司 2022-02-18 CN disclosed
US-20210254056-A1 IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS CAMP4 THERAPEUTICS CORPORATION 2021-08-19 US disclosed
US-20190192691-A1 REGULATED BIOCIRCUIT SYSTEMS OBSIDIAN THERAPEUTICS, INC. 2019-06-27 US disclosed
EP-2511844-B1 X-ray microscope XRPRO SCIENCES INC (US) 2015-08-12 EP disclosed
EP-2511844-A2 Advanced drug development and manufacturing Los Alamos National Security, LLC (US) 2012-10-17 EP disclosed
EP-2084519-B1 X-RAY FLUORESCENCE ANALYSIS METHOD LOS ALAMOS NAT SECURITY LLC (US) 2012-08-01 EP disclosed
EP-2084519-A2 ADVANCED DRUG DEVELOPMENT AND MANUFACTURING Los Alamos National Security, LLC (US) 2009-08-05 EP disclosed
WO-2008127291-A2 ADVANCED DRUG DEVELOPMENT AND MANUFACTURING LOS ALAMOS NATIONAL SECURITY, LLC (US) 2008-10-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12564722-B2 System and method for synchronizing energy delivery to the cardiac rhythm RYR2, ATP2A1, ATP2A2 SARS1 4034/4885LARS1 3657/4885TARS1 2429/4885
US-12582466-B2 Ablation assembly to treat target regions of tissue in organs ZYX, XBP1, PFKL SARS1 1611/4885LARS1 1243/4885TARS1 92/4885
US-12562230-B2 Memory device with high content density and encoding method thereof NCS1, HCN1, HCN2 SARS1 2841/4885LARS1 3961/4885TARS1 3473/4885
US-12508423-B2 Device for tissue electrotransfer using a microelectrode CUTA, EPCAM, CD69 SARS1 346/4885LARS1 996/4885TARS1 2803/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.