Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SARS1 | P49591 | 1/20 | 0.87 |
| ▸ | LARS1 | Q9P2J5 | 2/20 | 0.83 |
| ▸ | TARS1 | P26639 | 2/20 | 0.80 |
| ▸ | MARS1 | P56192 | 1/20 | 0.80 |
| ▸ | RARS1 | P54136 | 1/20 | 0.79 |
| ▸ | IARS1 | P41252 | 1/20 | 0.77 |
| ▸ | HARS1 | P12081 | 1/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21068060 | 1.00 | SARS1 (0.87) | SARS1LARS1TARS1MARS1RARS1 | |
| SCHEMBL3187637 | 1.00 | SARS1 (0.87) | SARS1LARS1TARS1MARS1RARS1 | |
| SCHEMBL4313369 | 0.93 | SARS1 (1.00) | SARS1LARS1TARS1MARS1RARS1 | |
| SCHEMBL21067959 | 0.93 | SARS1 (1.00) | SARS1LARS1TARS1MARS1RARS1 | |
| SCHEMBL178823 | 0.92 | SARS1 (0.85) | SARS1LARS1TARS1MARS1RARS1 | |
| SCHEMBL178824 | 0.92 | SARS1 (0.85) | SARS1LARS1TARS1MARS1RARS1 | |
| SCHEMBL30270578 | 0.92 | SARS1 (0.85) | SARS1LARS1TARS1MARS1RARS1 | |
| Leusa SCHEMBL29562511 | 0.91 | LARS1 (1.00) | SARS1LARS1TARS1MARS1RARS1 | |
| SCHEMBL13773209 | 0.91 | MARS1 (0.84) | SARS1LARS1TARS1MARS1RARS1 | |
| SCHEMBL13773211 | 0.91 | MARS1 (0.84) | SARS1LARS1TARS1MARS1RARS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100022509-A1 | Inhibitors of MshC and Homologs Thereof, and Methods of Identifying Same | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-01-28 | — | — | US | disclosed |
| WO-2008036139-A2 | INHIBITORS OF MSHC AND HOMOLOGS THEREOF, AND METHODS OF IDENTIFYING SAME | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-03-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100022509-A1 | Inhibitors of MshC and Homologs Thereof, and Methods of Identifying Same | ICMT, TST, OGA | SARS1 455/4885LARS1 741/4885TARS1 430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.